Lien vers Pubmed [PMID] – 32260196
Lien DOI – E54710.3390/biom10040547
Biomolecules 2020 04; 10(4):
The concept of pharmacological receptor was proposed at the turn of the 20th century but it took almost 70 years before the first receptor for a neurotransmitter was isolated and identified as a protein. This review retraces the history of the difficulties and successes in the identification of the nicotinic acetylcholine receptor, the first neurotransmitter receptor to be identified.