Lien vers Pubmed [PMID] – 32405102
Lien DOI – S0092-8674(20)30611-510.1016/j.cell.2020.05.016
Cell 2020 06; 181(6): 1194-1199
SARS-CoV-2 infection displays immense inter-individual clinical variability, ranging from silent infection to lethal disease. The role of human genetics in determining clinical response to the virus remains unclear. Studies of outliers-individuals remaining uninfected despite viral exposure and healthy young patients with life-threatening disease-present a unique opportunity to reveal human genetic determinants of infection and disease.