• 2024
  Fernández I, Saunders N, Duquerroy S, Bolland WH, Arbabian A, Baquero E, Blanc C, Lafaye P, Haouz A, Buchrieser J, Schwartz O, Rey FA, Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus., Cell 2024 Jun; (): .
• 2024
  David Fernandez-Martinez, Youxin Kong, Sylvie Goussard, Agustin Zavala, Pauline Gastineau, Martial Jean-Pierre Rey, Gabriel Ayme, Julia Chamot‐rooke, Pierre Lafaye, Matthijn Vos, Ariel Mechaly, Guillaume Duménil, Cryo-EM structures of type IV pili complexed with nanobodies reveal immune escape mechanisms, Nature Communications, 2024, 15 (1), pp.2414. ⟨10.1038/s41467-024-46677-y⟩.
• 2023
  Saunders N, Fernandez I, Planchais C, Michel V, Rajah MM, Baquero Salazar E, Postal J, Porrot F, Guivel-Benhassine F, Blanc C, Chauveau-Le Friec G, Martin A, Grzelak L, Oktavia RM, Meola A, Ahouzi O, Hoover-Watson H, Prot M, Delaune D, Cornelissen M, Deijs M, Meriaux V, Mouquet H, Simon-Lorière E, van der Hoek L, Lafaye P, Rey F, Buchrieser J, Schwartz O, TMPRSS2 is a functional receptor for human coronavirus HKU1., Nature 2023 Oct; (): .
• 2023
  Prevost MS, Barilone N, Dejean de la Bâtie G, Pons S, Ayme G, England P, Gielen M, Bontems F, Pehau-Arnaudet G, Maskos U, Lafaye P, Corringer PJ, An original potentiating mechanism revealed by the cryo-EM structures of the human α7 nicotinic receptor in complex with nanobodies., Nat Commun 2023 Sep; 14(1): 5964.
• 2023
  Céline Cuche, Marta Mastrogiovanni, Marie Juzans, Hélène Laude, Marie-Noëlle Ungeheuer, Daniel Krentzel, Maria Isabella Gariboldi, Daniel Scott-Algara, Marianne Madec, Sophie Goyard, Camille Floch, Gaëlle Chauveau-Le Friec, Pierre Lafaye, Charlotte Renaudat, Muriel Le Bidan, Christine Micallef, Sandrine Schmutz, Sébastien Mella, Sophie Novault, Milena Hasan, Darragh Duffy, Vincenzo Di Bartolo, Andrés Alcover, T cell migration and effector function differences in familial adenomatous polyposis patients with APC gene mutations, Frontiers in Immunology, 2023, 14, pp.1163466. ⟨10.3389/fimmu.2023.1163466⟩.
• 2023
  Li Q, Nemecz Á, Aymé G, Dejean de la Bâtie G, Prevost MS, Pons S, Barilone N, Baachaoui R, Maskos U, Lafaye P, Corringer PJ, Generation of nanobodies acting as silent and positive allosteric modulators of the α7 nicotinic acetylcholine receptor., Cell Mol Life Sci 2023 May; 80(6): 164.
• 2023
  Cawez F, Mercuri PS, Morales-Yãnez FJ, Maalouf R, Vandevenne M, Kerff F, Guérin V, Mainil J, Thiry D, Saulmont M, Vanderplasschen A, Lafaye P, Aymé G, Bogaerts P, Dumoulin M, Galleni M. , Development of Nanobodies as Theranostic Agents against CMY-2-Like Class C β-Lactamases., Antimicrob Agents Chemother. .
• 2022
  Gransagne M, Aymé G, Brier S, Chauveau-Le Friec G, Meriaux V, Nowakowski M, Dejardin F, Levallois S, Dias de Melo G, Donati F, Prot M, Brûlé S, Raynal B, Bellalou J, Goncalves P, Montagutelli X, Di Santo JP, Lazarini F, England P, Petres S, Escriou N, Lafaye P, , Development of a highly specific and sensitive VHH-based sandwich immunoassay for the detection of the SARS-CoV-2 nucleoprotein., J Biol Chem 2022 Jan; 298(1): 101290.
• 2021
  Moeglin E, Desplancq D, Stoessel A, Massute C, Ranniger J, McEwen AG, Zeder-Lutz G, Oulad-Abdelghani M, Chiper M, Lafaye P, Di Ventura B, Didier P, Poterszman A, Weiss E, , A Novel Nanobody Precisely Visualizes Phosphorylated Histone H2AX in Living Cancer Cells under Drug-Induced Replication Stress., Cancers (Basel) 2021 Jul; 13(13): .
• 2020
  Pothin E, Lesuisse D, Lafaye P, , Brain Delivery of Single-Domain Antibodies: A Focus on VHH and VNAR., Pharmaceutics 2020 Sep; 12(10): .
• 2019
  Lafaye P, Lesuisse D, Declèves X, , [New formats for improving brain drug delivery of antibodies: the blood-brain barrier case]., Med Sci (Paris) 2019 Dec; 35(12): 1106-1112.
• 2019
  da Costa A, Prehaud C, Bakoa F, Afonso P, Ceccaldi PE, Lafaye P, Lafon M, , A Human Blood-Brain Interface Model to Study Barrier Crossings by Pathogens or Medicines and Their Interactions with the Brain., J Vis Exp 2019 04; (146): .
• 2018
  Arthur Charles-Orszag, Feng-Ching Tsai, Daria Bonazzi, Valeria Manriquez, Martin Sachse, Adeline Mallet, Audrey Salles, Keira Melican, Ralitza Staneva, Aurélie Bertin, Corinne Millien, Sylvie Goussard, Pierre Lafaye, Spencer Shorte, Matthieu Piel, Jacomine Krijnse-Locker, Françoise Brochard-Wyart, Patricia Bassereau, Guillaume Duménil, Adhesion to nanofibers drives cell membrane remodeling through one-dimensional wetting, Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-018-06948-x⟩.
• 2018
  Barreto T, Alfonso Y, Lafaye P, García Lazaro MDP, Agueda Perez L, Herrera-Velit P, Espinoza JR, , [Single-chain antibodies from alpaca for the detection of Fasciola hepatica antigens]., Rev Peru Med Exp Salud Publica ; 35(4): 573-580.
• 2018
  Lafaye P, Li T, , Use of camel single-domain antibodies for the diagnosis and treatment of zoonotic diseases., Comp Immunol Microbiol Infect Dis 2018 Oct; 60(): 17-22.
• 2017
  Li T, Vandesquille M, Bay S, Dhenain M, Delatour B, Lafaye P, , Selection of similar single domain antibodies from two immune VHH libraries obtained from two alpacas by using different selection methods., Immunol Lett 2017 Aug; 188(): 89-95.
• 2017
  Magro L, Escadafal C, Garneret P, Jacquelin B, Kwasiborski A, Manuguerra JC, Monti F, Sakuntabhai A, Vanhomwegen J, Lafaye P, Tabeling P, , Paper microfluidics for nucleic acid amplification testing (NAAT) of infectious diseases., Lab Chip 2017 07; 17(14): 2347-2371.
• 2017
  Magro L, Jacquelin B, Escadafal C, Garneret P, Kwasiborski A, Manuguerra JC, Monti F, Sakuntabhai A, Vanhomwegen J, Lafaye P, Tabeling P, , Paper-based RNA detection and multiplexed analysis for Ebola virus diagnostics., Sci Rep 2017 05; 7(1): 1347.
• 2017
  Vandesquille M, Li T, Po C, Ganneau C, Lenormand P, Dudeffant C, Czech C, Grueninger F, Duyckaerts C, Delatour B, Dhenain M, Lafaye P, Bay S, , Chemically-defined camelid antibody bioconjugate for the magnetic resonance imaging of Alzheimer’s disease., MAbs 2017 ; 9(6): 1016-1027.
• 2016
  Li T, Vandesquille M, Koukouli F, Dudeffant C, Youssef I, Lenormand P, Ganneau C, Maskos U, Czech C, Grueninger F, Duyckaerts C, Dhenain M, Bay S, Delatour B, Lafaye P, , Camelid single-domain antibodies: A versatile tool for in vivo imaging of extracellular and intracellular brain targets., J Control Release 2016 Dec; 243(): 1-10.
• 2015
  Quaglio G, Goerens C, Putoto G, Rübig P, Lafaye P, Karapiperis T, Dario C, Delaunois P, Zachariah R, , Ebola: lessons learned and future challenges for Europe., Lancet Infect Dis 2016 Feb; 16(2): 259-63.
• 2015
  Delmaghani S, Defourny J, Aghaie A, Beurg M, Dulon D, Thelen N, Perfettini I, Zelles T, Aller M, Meyer A, Emptoz A, Giraudet F, Leibovici M, Dartevelle S, Soubigou G, Thiry M, Vizi ES, Safieddine S, Hardelin JP, Avan P, Petit C, Hypervulnerability to Sound Exposure through Impaired Adaptive Proliferation of Peroxisomes., Cell 2015 Nov; 163(4): 894-906.
• 2015
  M. Vandesquille, T. Li, F. Koukouli, C. Ganneau, U. Maskos, C. Czech, F. Grueninger, C. Duyckaerts, B. Delatour, S. Bay, P. Lafaye, M. Dhenain, New tools for amyloid plaques detection by MRI: Gadolinium-VHH antibody conjugates, 2014; 10, Supplement, P14–P15.
• 2014
  Gauthier C, Chassagne P, Theillet FX, Guerreiro C, Thouron F, Nato F, Delepierre M, Sansonetti PJ, Phalipon A, Mulard LA, Non-stoichiometric O-acetylation of Shigella flexneri 2a O-specific polysaccharide: synthesis and antigenicity, Org. Biomol. Chem. 2014 Jun;12(24):4218-32.
• 2013
  Tarr AW, Lafaye P, Meredith L, Damier-Piolle L, Urbanowicz RA, Meola A, Jestin JL, Brown RJ, McKeating JA, Rey FA, Ball JK, Krey T, An alpaca nanobody inhibits hepatitis C virus entry and cell-to-cell transmission, Hepatology 2013 Sep;58(3):932-9.
• 2013
  Terrade A, Collard JM, Nato F, Taha MK, Laboratory evaluation of a rapid diagnostic test for Neisseria meningitidis serogroup A., Trans R Soc Trop Med Hyg 2013 Jul; 107(7): 460-1.
• 2013
  Zarantonelli ML, Skoczynska A, Antignac A, El Ghachi M, Deghmane AE, Szatanik M, Mulet C, Werts C, Peduto L, d'Andon MF, Thouron F, Nato F, Lebourhis L, Philpott DJ, Girardin SE, Vives FL, Sansonetti P, Eberl G, Pedron T, Taha MK, Boneca IG, , Penicillin resistance compromises Nod1-dependent proinflammatory activity and virulence fitness of neisseria meningitidis., Cell Host Microbe 2013 Jun; 13(6): 735-45.
• 2012
  Pelleau S, Diop S, Dia Badiane M, Vitte J, Beguin P, Nato F, Diop BM, Bongrand P, Parzy D, Jambou R, , Enhanced basophil reactivities during severe malaria and their relationship with the Plasmodium falciparum histamine-releasing factor translationally controlled tumor protein., Infect Immun 2012 Aug; 80(8): 2963-70.
• 2012
  Li T, Bourgeois JP, Celli S, Glacial F, Le Sourd AM, Mecheri S, Weksler B, Romero I, Couraud PO, Rougeon F, Lafaye P, Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFP spontaneously cross the blood-brain barrier and specifically recognize astrocytes: application to brain imaging, FASEB J. 2012 Oct;26(10):3969-79.
• 2011
  Danne C, Entenza JM, Mallet A, Briandet R, Débarbouillé M, Nato F, Glaser P, Jouvion G, Moreillon P, Trieu-Cuot P, Dramsi S, Molecular characterization of a Streptococcus gallolyticus genomic island encoding a pilus involved in endocarditis, J. Infect. Dis. 2011 Dec;204(12):1960-70.
• 2009
  Perruchini C, Pecorari F, Bourgeois JP, Duyckaerts C, Rougeon F, Lafaye P, Llama VHH antibody fragments against GFAP: better diffusion in fixed tissues than classical monoclonal antibodies, Acta Neuropathol. 2009 Nov;118(5):685-95.
• 2008
  Lafaye P, Achour I, England P, Duyckaerts C, Rougeon F, Single-domain antibodies recognize selectively small oligomeric forms of amyloid beta, prevent Abeta-induced neurotoxicity and inhibit fibril formation, Mol. Immunol. 2009 Feb;46(4):695-704.
• 2008
  Vigan-Womas I, Guillotte M, Le Scanf C, Igonet S, Petres S, Juillerat A, Badaut C, Nato F, Schneider A, Lavergne A, Contamin H, Tall A, Baril L, Bentley GA, Mercereau-Puijalon O, An in vivo and in vitro model of Plasmodium falciparum rosetting and autoagglutination mediated by varO, a group A var gene encoding a frequent serotype, Infect. Immun. 2008 Dec;76(12):5565-80.
• 2008
  Achour I, Cavelier P, Tichit M, Bouchier C, Lafaye P, Rougeon F, Tetrameric and homodimeric camelid IgGs originate from the same IgH locus, J. Immunol. 2008 Aug;181(3):2001-9.
• 2008
  Ahmed F, André-Leroux G, Haouz A, Boutonnier A, Delepierre M, Qadri F, Nato F, Fournier JM, Alzari PM, Crystal structure of a monoclonal antibody directed against an antigenic determinant common to Ogawa and Inaba serotypes of Vibrio cholerae O1, Proteins 2008 Jan;70(1):284-8.
• 2007
  Nato F, Phalipon A, Nguyen TL, Diep TT, Sansonetti P, Germani Y, Dipstick for rapid diagnosis of Shigella flexneri 2a in stool, PLoS ONE 2007;2(4):e361.
• 2006
  Rouis S, Lafaye P, Jaoua-Aydi L, Sghaier Z, Ayadi H, Gargouri-Bouzid R, Cloning and expression of functional single-chain Fv antibodies directed against NIa and coat proteins of potato virus Y, J. Virol. Methods 2006 Oct;137(1):1-6.
• 2006
  Phalipon A, Costachel C, Grandjean C, Thuizat A, Guerreiro C, Tanguy M, Nato F, Vulliez-Le Normand B, Bélot F, Wright K, Marcel-Peyre V, Sansonetti PJ, Mulard LA, Characterization of functional oligosaccharide mimics of the Shigella flexneri serotype 2a O-antigen: implications for the development of a chemically defined glycoconjugate vaccine, J. Immunol. 2006 Feb;176(3):1686-94.
• 2004
  Trap C, Nato F, Chalbot S, Kim SB, Lafaye P, Morfin R, Immunohistochemical detection of the human cytochrome P4507B1: production of a monoclonal antibody after cDNA immunization, J. Neuroimmunol. 2005 Feb;159(1-2):41-7.
• 2004
  Brossier F, Lévy M, Landier A, Lafaye P, Mock M, Functional analysis of Bacillus anthracis protective antigen by using neutralizing monoclonal antibodies, Infect. Immun. 2004 Nov;72(11):6313-7.
• 2004
  Bay S, Huteau V, Zarantonelli ML, Pires R, Ughetto-Monfrin J, Taha MK, England P, Lafaye P, , Phosphorylcholine-carbohydrate-protein conjugates efficiently induce hapten-specific antibodies which recognize both Streptococcus pneumoniae and Neisseria meningitidis: a potential multitarget vaccine against respiratory infections., J Med Chem 2004 Jul; 47(16): 3916-9.
• 2003
  Pizarro JC, Chitarra V, Verger D, Holm I, Pêtres S, Dartevelle S, Nato F, Longacre S, Bentley GA, Crystal structure of a Fab complex formed with PfMSP1-19, the C-terminal fragment of merozoite surface protein 1 from Plasmodium falciparum: a malaria vaccine candidate, J. Mol. Biol. 2003 May;328(5):1091-103.
• 2003
  Ehsani P, Meunier A, Nato F, Jafari A, Nato A, Lafaye P, Expression of anti human IL-4 and IL-6 scFvs in transgenic tobacco plants, Plant Mol. Biol. 2003 May;52(1):17-29.
• 2003
  Chanteau S, Rahalison L, Ralafiarisoa L, Foulon J, Ratsitorahina M, Ratsifasoamanana L, Carniel E, Nato F, Development and testing of a rapid diagnostic test for bubonic and pneumonic plague, Lancet 2003 Jan;361(9353):211-6.
• 2003
  Muzerelle A, Alberts P, Martinez-Arca S, Jeannequin O, Lafaye P, Mazié JC, Galli T, Gaspar P, Tetanus neurotoxin-insensitive vesicle-associated membrane protein localizes to a presynaptic membrane compartment in selected terminal subsets of the rat brain, Neuroscience 2003;122(1):59-75.
• 2001
  Thullier P, Demangel C, Bedouelle H, Mégret F, Jouan A, Deubel V, Mazié JC, Lafaye P, Mapping of a dengue virus neutralizing epitope critical for the infectivity of all serotypes: insight into the neutralization mechanism, J. Gen. Virol. 2001 Aug;82(Pt 8):1885-92.
• 2001
  Seddiki N, Nato F, Lafaye P, Amoura Z, Piette JC, Mazié JC, Calreticulin, a potential cell surface receptor involved in cell penetration of anti-DNA antibodies, J. Immunol. 2001 May;166(10):6423-9.
• 2000
  Cardoso DF, Nato F, England P, Ferreira ML, Vaughan TJ, Mota I, Mazie JC, Choumet V, Lafaye P, Neutralizing human anti crotoxin scFv isolated from a nonimmunized phage library, Scand. J. Immunol. 2000 Apr;51(4):337-44.
• 2000
  Morfin R, Lafaye P, Cotillon AC, Nato F, Chmielewski V, Pompon D, 7 alpha-hydroxy-dehydroepiandrosterone and immune response, Ann. N. Y. Acad. Sci. 2000;917:971-82.
• 1999
  Lafaye P, Chmielewski V, Nato F, Mazié JC, Morfin R, The 7alpha-hydroxysteroids produced in human tonsils enhance the immune response to tetanus toxoid and Bordetella pertussis antigens, Biochim. Biophys. Acta 1999 Oct;1472(1-2):222-31.
• 1999
  Braun L, Nato F, Payrastre B, Mazié JC, Cossart P, The 213-amino-acid leucine-rich repeat region of the listeria monocytogenes InlB protein is sufficient for entry into mammalian cells, stimulation of PI 3-kinase and membrane ruffling, Mol. Microbiol. 1999 Oct;34(1):10-23.
• 1999
  Létoffé S, Nato F, Goldberg ME, Wandersman C, Interactions of HasA, a bacterial haemophore, with haemoglobin and with its outer membrane receptor HasR, Mol. Microbiol. 1999 Aug;33(3):546-55.
• 1999
  Choumet V, Lafaye P, Demangel C, Bon C, Mazié JC, Molecular mimicry between a monoclonal antibody and one subunit of crotoxin, a heterodimeric phospholipase A2 neurotoxin, Biol. Chem. 1999 May;380(5):561-8.
• 1999
  Thullier P, Lafaye P, Mégret F, Deubel V, Jouan A, Mazié JC, A recombinant Fab neutralizes dengue virus in vitro, J. Biotechnol. 1999 Apr;69(2-3):183-90.
• 1998
  Choumet V, Lafaye P, Mazié JC, Bon C, A monoclonal antibody directed against the non-toxic subunit of a dimeric phospholipase A2 neurotoxin, crotoxin, neutralizes its toxicity, Biol. Chem. 1998 Jul;379(7):899-906.
• 1998
  Wang J, Villeneuve S, Zhang J, Lei P, Miller CE, Lafaye P, Nato F, Szu SC, Karpas A, Bystricky S, Robbins JB, Kovác P, Fournier JM, Glaudemans CP, On the antigenic determinants of the lipopolysaccharides of Vibrio cholerae O:1, serotypes Ogawa and Inaba, J. Biol. Chem. 1998 Jan;273(5):2777-83.
• 1998
  Demangel C, Rouyre S, Alzari PM, Nato F, Longacre S, Lafaye P, Mazie JC, Phage-displayed mimotopes elicit monoclonal antibodies specific for a malaria vaccine candidate, Biol. Chem. 1998 Jan;379(1):65-70.
• 1997
  Muller BH, Lafay F, Demangel C, Perrin P, Tordo N, Flamand A, Lafaye P, Guesdon JL, Phage-displayed and soluble mouse scFv fragments neutralize rabies virus, J. Virol. Methods 1997 Sep;67(2):221-33.
• 1997
  Lafaye P, Choumet V, Demangel C, Bon C, Mazié JC, Biologically active human anti-crotoxin scFv isolated from a semi-synthetic phage library, Immunotechnology 1997 Jun;3(2):117-25.
• 1996
  Demangel C, Lafaye P, Mazie JC, Reproducing the immune response against the Plasmodium vivax merozoite surface protein 1 with mimotopes selected from a phage-displayed peptide library, Mol. Immunol. 1996 Aug;33(11-12):909-16.
• 1996
  Lebrun M, Mengaud J, Ohayon H, Nato F, Cossart P, Internalin must be on the bacterial surface to mediate entry of Listeria monocytogenes into epithelial cells, Mol. Microbiol. 1996 Aug;21(3):579-92.
• 1996
  Lafaye P, Nato F, Mazié JC, Doyen N, Similar binding properties for a neutralizing anti-tetanus toxoid human monoclonal antibody and its bacterially expressed Fab, Res. Immunol. 1996 Jan;147(1):61.
• 1995
  Lafaye P, Nato F, Mazié JC, Doyen N, Similar binding properties for a neutralizing anti-tetanus toxoid human monoclonal antibody and its bacterially expressed Fab, Res. Immunol. 1995 Jul-Aug;146(6):373-82.
• 1995
  Smith LA, Olson MA, Lafaye PJ, Dolly JO, Cloning and expression of mamba toxins, Toxicon 1995 Apr;33(4):459-74.
• 1993
  Smith LA, Lafaye PJ, LaPenotiere HF, Spain T, Dolly JO, Cloning and functional expression of dendrotoxin K from black mamba, a K+ channel blocker, Biochemistry 1993 Jun;32(21):5692-7.
• 1993
  Canica MM, Nato F, du Merle L, Mazie JC, Baranton G, Postic D, Monoclonal antibodies for identification of Borrelia afzelii sp. nov. associated with late cutaneous manifestations of Lyme borreliosis, Scand. J. Infect. Dis. 1993;25(4):441-8.
• 1991
  Nato F, Reich K, Lhopital S, Rouyre S, Geoffroy C, Mazie JC, Cossart P, Production and characterization of neutralizing and nonneutralizing monoclonal antibodies against listeriolysin O, Infect. Immun. 1991 Dec;59(12):4641-6.
• 1990
  Emod I, Lafaye P, Planchenault T, Lambert Vidmar S, Imhoff JM, Keil-Dlouha V, Potential proteolytic activity of fibronectin: fibronectin laminase and its substrate specificity, Biol. Chem. Hoppe-Seyler 1990 Feb;371(2):129-35.
• 1988
  Lafaye P, Lapresle C, Identification of two fixation sites for penicilloyl groups on the albumin molecule from penicillin-treated patients, FEBS Lett. 1988 Jul;234(2):305-8.
• 1988
  Lafaye P, Lapresle C, Fixation of penicilloyl groups to albumin and appearance of anti-penicilloyl antibodies in penicillin-treated patients, J. Clin. Invest. 1988 Jul;82(1):7-12.
• 1987
  Lafaye P, Lapresle C, Location of penicilloyl groups on CNBr fragments of the albumin from penicillin-treated patients, FEBS Lett. 1987 Aug;220(1):206-8.
• 1985
  Lapresle C, Lafaye P, Enzyme-linked immunosorbent assay for measurement of penicilloyl groups, Ann. Inst. Pasteur Immunol. 1985 May-Jun;136C(3):375-82.
• 1985
  Doyen N, Lapresle C, Lafaye P, Mazie JC, Study of the antigenic structure of human serum albumin with monoclonal antibodies, Mol. Immunol. 1985 Jan;22(1):1-10.