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2023A human immune system (HIS) mouse model that dissociates roles for mouse and human FcR+ cells during antibody-mediated immune responses., Eur J Immunol 2023 Aug; (): e2350454.
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2021Animal Models for Hepatitis B: Does the Supply Meet the Demand?, Gastroenterology 2021 April;160(5):1437-42 .
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2020Potent human broadly neutralizing antibodies to hepatitis B virus from natural controllers., J. Exp. Med. 2020 ; 217(10): .
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2020In-vitro and in-vivo models for hepatitis B cure research, Curr Opin HIV AIDS 2020 Feb;.
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2020Novel Hepatitis B Virus Capsid Assembly Modulator Induces Potent Antiviral Responses In Vitro and in Humanized Mice., Antimicrob Agents Chemother 2020 01; 64(2): .
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2019Accelerated thymopoiesis and improved T-cell responses in HLA-A2/-DR2 transgenic BRGS-based human immune system mice., Eur J Immunol 2019 06; 49(6): 954-965.
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2018Who Defends the Stem Cell’s Citadel?, Cell Stem Cell 2018 Mar;22(3):287-289.
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2017Regulatory T cells control toxicity in a humanized model of IL-2 therapy, Nat Commun 2017 11;8(1):1762.
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2017Modeling hepatitis virus infections and treatment strategies in humanized mice, Curr Opin Virol 2017 Aug;25:119-125.
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2017Viral Load Affects the Immune Response to HBV in Mice With Humanized Immune System and Liver., Gastroenterology 2017 12; 153(6): 1647-1661.e9.
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2017A functional DC cross talk promotes human ILC homeostasis in humanized mice., Blood Adv 2017 Apr; 1(10): 601-614.
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2017Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation., Cell 2017 03; 168(6): 1086-1100.e10.
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2016A novel Flt3-deficient HIS mouse model with selective enhancement of human DC development., Eur J Immunol 2016 05; 46(5): 1291-9.
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2016Progressive developmental restriction, acquisition of left-right identity and cell growth behavior during lobe formation in mouse liver development, Development 2016 Apr;143(7):1149-59.
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2015A novel mouse model for stable engraftment of a human immune system and human hepatocytes., PLoS One 2015 ; 10(3): e0119820.
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2015Towards an HBV cure: state-of-the-art and unresolved questions–report of the ANRS workshop on HBV cure, Gut 2015 Aug;64(8):1314-26.
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2014Animal models to test hiPS-derived hepatocytes in the context of inherited metabolic liver diseases., Methods Mol Biol 2014 ; 1213(): 81-8.
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2012Ectopic expression of murine CD47 minimizes macrophage rejection of human hepatocyte xenografts in immunodeficient mice, Hepatology 2012 Oct;56(4):1479-88.
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2012Production of hepatitis B defective particles is dependent on liver status, Virology 2012 Sep 15-30;431(1-2):21-8.
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2011Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells, Nature 2011 Oct;478(7369):391-4.
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2011Autonomous and extrinsic regulation of thymopoiesis in human immune system (HIS) mice, Eur. J. Immunol. 2011 Oct;41(10):2883-93.
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2011Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo, Proc. Natl. Acad. Sci. U.S.A. 2011 Aug;108(32):13224-9.
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2011IL-15 transpresentation promotes both human T-cell reconstitution and T-cell-dependent antibody responses in vivo, Proc. Natl. Acad. Sci. U.S.A. 2011 Apr;108(15):6217-22.
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2010Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development, Hepatology 2010 May;51(5):1754-65.
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2009Humanized mice for modeling human infectious disease: challenges, progress, and outlook, Cell Host Microbe 2009 Jul;6(1):5-9.
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2008Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer, Cancer Cell 2008 Dec;14(6):471-84.
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2008Lymphocytes support oval cell-dependent liver regeneration, J. Immunol. 2008 Aug;181(4):2764-71.
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2008Morphogenetic competence of HNF4 alpha-deficient mouse hepatic cells, J. Hepatol. 2008 Sep;49(3):384-95.
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2007Gamma c cytokines condition the progressive differentiation of CD4+ T cells, Proc. Natl. Acad. Sci. U.S.A. 2007 Sep;104(39):15442-7.
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2007gamma(c) cytokines provide multiple homeostatic signals to naive CD4(+) T cells, Eur. J. Immunol. 2007 Sep;37(9):2606-16.
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2007The JNK/AP-1 pathway upregulates expression of the recycling endosome rab11a gene in B cells transformed by Theileria., Cell Microbiol 2007 Aug; 9(8): 1936-45.
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2007Transcriptional profiling of bipotential embryonic liver cells to identify liver progenitor cell surface markers, Stem Cells 2007 Oct;25(10):2476-87.
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2006Plasticity of hepatic cell differentiation: bipotential adult mouse liver clonal cell lines competent to differentiate in vitro and in vivo, Stem Cells 2006 Sep;24(9):2098-109.
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2004Transcription factor HNF-6/OC-1 inhibits the stimulation of the HNF-3alpha/Foxa1 gene by TGF-beta in mouse liver, Hepatology 2004 Dec;40(6):1266-74.
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2004Bipotential mouse embryonic liver stem cell lines contribute to liver regeneration and differentiate as bile ducts and hepatocytes, Proc. Natl. Acad. Sci. U.S.A. 2004 Jun;101(22):8360-5.
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2003Isolation and characterization of mouse hepatic stem cells in vitro, Semin. Liver Dis. 2003 Nov;23(4):313-24.
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2003Embryonic liver cells and permanent lines as models for hepatocyte and bile duct cell differentiation, Mech. Dev. 2003 Jan;120(1):89-98.
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2002Inducible differentiation and morphogenesis of bipotential liver cell lines from wild-type mouse embryos, Hepatology 2002 Oct;36(4 Pt 1):794-804.