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2023Targeting structural flexibility in low density lipoprotein by integrating cryo-electron microscopy and high-speed atomic force microscopy., Int J Biol Macromol 2023 Aug; 252(): 126345.
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2022Morphological control enables nanometer-scale dissection of cell-cell signaling complexes., Nat Commun 2022 Dec; 13(1): 7831.
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2022MEPSi: A tool for simulating tomograms of membrane-embedded proteins., J Struct Biol 2022 Dec; 214(4): 107921.
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2022Characterization of heterogeneity in nanodisc samples using Feret signatures., J Struct Biol 2022 Dec; 214(4): 107916.
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2022Novel cryo-tomography workflow reveals nanometer-scale responses of epithelial cells to matrix stiffness and dimensionality., Mol Biol Cell 2022 Oct; (): mbcE22030092.
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2022ECM dimensionality tunes actin tension to modulate endoplasmic reticulum function and spheroid phenotypes of mammary epithelial cells., EMBO J 2022 09; 41(17): e109205.
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2022Novel ACE2 nanoparticles universally block SARS-CoV-2 variants in the human respiratory tract, 2023.
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2022The complexin C-terminal amphipathic helix stabilizes the fusion pore open state by sculpting membranes., Nat Struct Mol Biol 2022 02; 29(2): 97-107.
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2021Rapid tool for cell nanoarchitecture integrity assessment., J Struct Biol 2021 12; 213(4): 107801.
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2021The actomyosin interface contains an evolutionary conserved core and an ancillary interface involved in specificity., Nat Commun 2021 03; 12(1): 1892.
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2020Structural basis of αE-catenin-F-actin catch bond behavior., Elife 2020 09; 9(): .
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2020Factor VIII exhibits chaperone-dependent and glucose-regulated reversible amyloid formation in the endoplasmic reticulum., Blood 2020 05; 135(21): 1899-1911.
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2019Extracellular matrix micropatterning technology for whole cell cryogenic electron microscopy studies., J Micromech Microeng 2019 Nov; 29(11): .
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2019High Rac1 activity is functionally translated into cytosolic structures with unique nanoscale cytoskeletal architecture., Proc Natl Acad Sci U S A 2019 01; 116(4): 1267-1272.
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2019Biophysical Characterization of a Nanodisc with and without BAX: An Integrative Study Using Molecular Dynamics Simulations and Cryo-EM., Structure 2019 06; 27(6): 988-999.e4.
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2019Electron cryo-tomography of vestibular hair-cell stereocilia., J Struct Biol 2019 05; 206(2): 149-155.
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2018Does self-organized criticality drive leading edge protrusion?, Biophys Rev 2018 Dec; 10(6): 1571-1575.
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2018Local Tension on Talin in Focal Adhesions Correlates with F-Actin Alignment at the Nanometer Scale., Biophys J 2018 10; 115(8): 1569-1579.
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2018Matrix vesicles from chondrocytes and osteoblasts: Their biogenesis, properties, functions and biomimetic models., Biochim Biophys Acta Gen Subj 2018 Mar; 1862(3): 532-546.
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2018Marker-free method for accurate alignment between correlated light, cryo-light, and electron cryo-microscopy data using sample support features., J Struct Biol 2018 01; 201(1): 46-51.
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2018Conformational Equilibrium of Human Platelet Integrin Investigated by Three-Dimensional Electron Cryo-Microscopy., Subcell Biochem 2018 ; 87(): 353-363.
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2017Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos., Nat Commun 2017 11; 8(1): 1439.
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2017Tunneling Nanotubes and Gap Junctions-Their Role in Long-Range Intercellular Communication during Development, Health, and Disease Conditions., Front Mol Neurosci 2017 ; 10(): 333.
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2017Nano-scale actin-network characterization of fibroblast cells lacking functional Arp2/3 complex., J Struct Biol 2017 03; 197(3): 312-321.
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2016Structure of anthrax lethal toxin prepore complex suggests a pathway for efficient cell entry., J Gen Physiol 2016 10; 148(4): 313-24.
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2016Three-Dimensional Structures of Full-Length, Membrane-Embedded Human α(IIb)β(3) Integrin Complexes., Biophys J 2016 Feb; 110(4): 798-809.
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2015Orchestration of ErbB3 signaling through heterointeractions and homointeractions., Mol Biol Cell 2015 Nov; 26(22): 4109-23.
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2015The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells., PLoS Biol 2015 10; 13(10): e1002277.
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2015Validation methods for low-resolution fitting of atomic structures to electron microscopy data., Arch Biochem Biophys 2015 Sep; 581(): 49-53.
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2015Efficient Extraction of Macromolecular Complexes from Electron Tomograms Based on Reduced Representation Templates., Comput Anal Images Patterns 2015 Sep; 9256(): 423-431.
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2015Accurate membrane tracing in three-dimensional reconstructions from electron cryotomography data., Ultramicroscopy 2015 Aug; 155(): 20-26.
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2015Cellular chirality arising from the self-organization of the actin cytoskeleton., Nat Cell Biol 2015 Apr; 17(4): 445-57.
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2015A mechanism of leading-edge protrusion in the absence of Arp2/3 complex., Mol Biol Cell 2015 Mar; 26(5): 901-12.
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2014Cell adhesion. The minimal cadherin-catenin complex binds to actin filaments under force., Science 2014 Oct; 346(6209): 1254211.
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2014Three-dimensional reconstructions of actin filaments capped by Arp2/3 complex., Eur J Cell Biol ; 93(5-6): 179-83.
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2014Holoenzyme structures of endothelial nitric oxide synthase – an allosteric role for calmodulin in pivoting the FMN domain for electron transfer., J Struct Biol 2014 Oct; 188(1): 46-54.
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2014The joys and perils of flexible fitting., Adv Exp Med Biol 2014 ; 805(): 137-55.
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2013αE-catenin actin-binding domain alters actin filament conformation and regulates binding of nucleation and disassembly factors., Mol Biol Cell 2013 Dec; 24(23): 3710-20.
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2013The architectural relationship of components controlling mast cell endocytosis., J Cell Sci 2013 Nov; 126(Pt 21): 4913-25.
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2013Probabilistic determination of probe locations from distance data., J Struct Biol 2013 Oct; 184(1): 75-82.
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2013Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: implications for talin activation., J Struct Biol 2013 Oct; 184(1): 21-32.
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2012Toxofilin upregulates the host cortical actin cytoskeleton dynamics, facilitating Toxoplasma invasion., J Cell Sci 2012 Sep; 125(Pt 18): 4333-42.
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2012Electron tomographic analysis of synaptic ultrastructure., J Comp Neurol 2012 Aug; 520(12): 2697-711.
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2012The C-terminal tail domain of metavinculin, vinculin’s splice variant, severs actin filaments., J Cell Biol 2012 May; 197(5): 585-93.
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2012Key structural features of the actin filament Arp2/3 complex branch junction revealed by molecular simulation., J Mol Biol 2012 Feb; 416(1): 148-61.
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2012Putting structure into context: fitting of atomic models into electron microscopic and electron tomographic reconstructions., Curr Opin Cell Biol 2012 Feb; 24(1): 141-7.
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2012Three-dimensional reconstructions of Arp2/3 complex with bound nucleation promoting factors., EMBO J 2012 Jan; 31(1): 236-47.
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2011Correlative light-electron microscopy., Adv Protein Chem Struct Biol 2011 ; 82(): 91-9.
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2010Molecular basis for the dual function of Eps8 on actin dynamics: bundling and capping., PLoS Biol 2010 Jun; 8(6): e1000387.
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2010Carboxylated N-glycans on RAGE promote S100A12 binding and signaling., J Cell Biochem 2010 Jun; 110(3): 645-59.
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2010Methods for segmentation and interpretation of electron tomographic reconstructions., Methods Enzymol 2010 ; 483(): 31-46.
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2009Confidence intervals for fitting of atomic models into low-resolution densities., Acta Crystallogr D Biol Crystallogr 2009 Jul; 65(Pt 7): 679-89.
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2008Segmentation of electron tomographic data sets using fuzzy set theory principles., J Struct Biol 2008 Jun; 162(3): 368-79.
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2008Three-dimensional architecture of hair-bundle linkages revealed by electron-microscopic tomography., J Assoc Res Otolaryngol 2008 Jun; 9(2): 215-24.
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2008The structural basis of actin filament branching by the Arp2/3 complex., J Cell Biol 2008 Mar; 180(5): 887-95.
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2008The structure of the C-terminal actin-binding domain of talin., EMBO J 2008 Jan; 27(2): 458-69.
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2007The R403Q myosin mutation implicated in familial hypertrophic cardiomyopathy causes disorder at the actomyosin interface., PLoS One 2007 Nov; 2(11): e1123.
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2007Evidence for an interaction between the SH3 domain and the N-terminal extension of the essential light chain in class II myosins., J Mol Biol 2007 Aug; 371(4): 902-13.
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2007Effect of calcium on calmodulin bound to the IQ motifs of myosin V., J Biol Chem 2007 Aug; 282(32): 23316-25.
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2007Efficient automatic noise reduction of electron tomographic reconstructions based on iterative median filtering., J Struct Biol 2007 May; 158(2): 196-204.
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2007Density-based score for selecting near-native atomic models of unknown structures., J Struct Biol 2007 May; 158(2): 188-95.
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2007Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation., Mol Cell 2007 Mar; 25(5): 713-24.
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2006Type IV pilus structure by cryo-electron microscopy and crystallography: implications for pilus assembly and functions., Mol Cell 2006 Sep; 23(5): 651-62.
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2006Three-dimensional structure of vinculin bound to actin filaments., Mol Cell 2006 Jan; 21(2): 271-81.
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2005Mechanism of filament nucleation and branch stability revealed by the structure of the Arp2/3 complex at actin branch junctions., PLoS Biol 2005 Nov; 3(11): e383.
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2005The structural basis of myosin V processive movement as revealed by electron cryomicroscopy., Mol Cell 2005 Sep; 19(5): 595-605.
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2005Effects of Arp2 and Arp3 nucleotide-binding pocket mutations on Arp2/3 complex function., J Cell Biol 2005 Jan; 168(2): 315-28.
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2004An approach to automated particle picking from electron micrographs based on reduced representation templates., J Struct Biol ; 145(1-2): 152-6.
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2004Automatic particle selection: results of a comparative study., J Struct Biol ; 145(1-2): 3-14.
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2004Characterization of an actin-binding site within the talin FERM domain., J Mol Biol 2004 Oct; 343(3): 771-84.
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2004Direct continuities between cisternae at different levels of the Golgi complex in glucose-stimulated mouse islet beta cells., Proc Natl Acad Sci U S A 2004 Apr; 101(15): 5565-70.
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2003Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2., EMBO J 2003 Sep; 22(17): 4566-76.
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2003Myosin isoforms show unique conformations in the actin-bound state., Proc Natl Acad Sci U S A 2003 Mar; 100(6): 3227-32.
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2003Docking of atomic models into reconstructions from electron microscopy., Methods Enzymol 2003 ; 374(): 204-25.
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2003Electron microscopy., Methods Biochem Anal 2003 ; 44(): 115-33.
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2002Microscopic evidence for a minus-end-directed power stroke in the kinesin motor ncd., EMBO J 2002 Nov; 21(22): 5969-78.
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2002A novel three-dimensional variant of the watershed transform for segmentation of electron density maps., J Struct Biol ; 138(1-2): 123-9.
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2002Arp2/3 plays no role in muscle contraction., Nature 2002 Aug; 418(6901): 915.