Lien vers Pubmed [PMID] – 10322146
Curr. Opin. Immunol. 1999 Apr;11(2):152-6
T cell survival in the periphery is an active process, depending on continuous TCR engagement by peptide-MHC complexes and/or response to environmental cytokines. Naive T cells require interactions with the MHC restricting element. The survival requirements of memory T cells are as yet insufficiently characterized, but MHC-restricted interactions are not necessary.