Lien vers Pubmed [PMID] – 11907329
J. Gen. Virol. 2002 Apr;83(Pt 4):801-5
Two full-length human immunodeficiency virus type 1 O sequences are described, one of which was hypermutated in all regions of the genome. This indicates that the intracellular [dTTP]/[dCTP] bias conducive to G–>A hypermutation may be sustained throughout the synthesis of minus-strand DNA. In turn, this suggests the possibility of mutation of host sequences.