Lien vers Pubmed [PMID] – 40973531
Lien DOI – 10.1016/j.it.2025.09.005
Trends Immunol 2025 Sep; ():
Immune activity at the cerebrospinal fluid (CSF)-dura-brain interface regulates key functions of brain physiology. In two back-to-back papers, Mamuladze et al. and Kothari et al. show that dural mast cells (MCs) are strategically positioned to coordinate this regulation, controlling CSF flow dynamics and immune cell trafficking in allergy, meningitis, and stroke.