Main domain : Cellular & molecular neurosciences Subdomain : Clinical & translational neurosciences Séverine BOILLEE’s team investigates mechanisms of motor neuron (MN) degeneration in Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig’s disease) resulting from […]
Research work My work aims to study the mechanisms leading to motor neuron degeneration and death in Amyotrophic Lateral Sclerosis (ALS) using iPSC models. ALS is a heterogeneous disease under different aspects (genetic, clinical). […]
Director Frédéric Relaix Scientific projects Muscle stem cells in the forefront of myogenesis Interactions of stem cells with their environment Pathogenesis and therapy of neuromuscular disorders Neural crest cell plasticity, migration and fate Stem […]
Team director : Biology of the neuromuscular system Institut Mondor de recherche Biomédicale UMR U955 – INSERM – UPEC Faculté de Santé de Créteil 8 rue du Général Sarrail 94010 Créteil cedex Tél. : […]
Director : Raphael Scharfmann Team website Pancreatic beta cells are specialized factories devoted to produce large amounts of insulin that is stored within granules and secreted in a tightly regulated fashion. In the pancreas, […]
Functional pancreatic beta cell mass in rodent and human Pancreatic beta cells are specialized factories devoted to produce large amounts of insulin that is stored within granules and secreted in a tightly regulated fashion. […]
Our objective is still to develop a cell therapy product targeted at the repair of the chronically failing myocardium and based on the use of cardiac progenitor cells derived from induced pluripotent stem cells. […]
Philippe Menasché Department of Cardiovascular Surgery INSERM U970 – Hôpital Européen Georges Pompidou 20, rue Leblanc 75015 Paris Tel +33 1 5609 3622/2962 Fax +33 1 5609 3261 philippe.menasche@egp.aphp.fr Laboratory Website Our objective is […]
OUR OBJECTIVES Understanding the early stages of the development of mammalian embryos from fertilisation to the establishment of the first differentiation events. To this end, a multi-species approach is used by studying mainly bovine, […]
Team website : Embryo and Pluripotency : Epigenetic and Environment (EPEE) Labex Revive partner
I have been a particular curiosity about how I can get more details about inside cells. For many years, I have been gathering many data about What happens inner cells when they start to […]
The lack of pertinent models for neuromuscular disorders has rendered many important questions in disease pathogenesis inaccessible. Current drugs provide only limited benefit by alleviating certain symptoms. Clearly, the development of efficacious preventive or […]
Cécile Martinat is director of the Institute of Stem Cells for the Treatment and Study of Monogenic Diseases (I-Stem – Université Paris-Saclay, Inserm, Université d’Évry). She is also President of the French Society for […]
Cecile Martinat is director of the Institute of Stem Cells for the Treatment and Study of Monogenic Diseases (I-Stem – Université Paris-Saclay, Inserm, Université d’Évry). In 2016, she was elected President of the French […]