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© Research
Publication : Protein and peptide letters

Unexpected altered specificity is responsible for St. Louis encephalitis virus recombinant protease autoproteolysis

Team: Archived: Biology of Enteric Viruses
Member: Maël Bessaud
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Protein and peptide letters - 01 Jan 2007

Pastorino BA, Peyrefitte CN, Grandadam M, Lebrun R, Moinier D, Rolland D, Tolou HJ, Bessaud M

Link to Pubmed [PMID] – 17266653

Protein Pept. Lett. 2007;14(1):79-82

We report herein the study of the cleavage fragments generated by autoproteolysis of the St. Louis encephalitis virus recombinant protease. The cleavage sites leading to truncated forms were identified by microsequencing, which revealed an unexpected altered specificity of the recombinant proteinase towards unusual sequences.