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© Research
Publication : Trends in parasitology

Theoretical Implications of a Pre-Erythrocytic Plasmodium vivax Vaccine for Preventing Relapses

Team: Malaria Infection & Immunity
Team: Archived: Malaria : parasites and hosts
Member: Rogerio Amino
Member: Michael White
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Trends in parasitology - 08 Jan 2017

White M, Amino R, Mueller I

Link to Pubmed [PMID] – 28077251

Trends Parasitol. 2017 04;33(4):260-263

Preventing malaria infection through vaccination requires preventing every sporozoite inoculated by mosquito bite: a major challenge for Plasmodium falciparum. Plasmodium vivax sporozoites consist of tachysporozoites causing primary infection and bradysporozoites leading to relapses. We hypothesise that a candidate P. vivax vaccine with low efficacy against primary infection may substantially reduce transmission by preventing relapses.