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© Research
Publication : Journal of motor behavior

Saccadic Eye Movements in Patients with Mild Cognitive Impairment: A Longitudinal Study.

Member: Koray Koçoglu
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of motor behavior - 01 Jan 2023

Akkoyun M, Koçoğlu K, Eraslan Boz H, Keskinoğlu P, Akdal G

Link to Pubmed [PMID] – 37080551

Link to DOI – 10.1080/00222895.2023.2202620

J Mot Behav 2023 ; 55(4): 354-372

Saccadic eye movements are one of the sensitive and noninvasive methods to help monitor the cognitive course of mild cognitive impairment (MCI). The study aimed to evaluate both pro and anti-saccade longitudinally and the relationship between cognitive functions and eye movements in MCI subgroups and healthy controls (HCs) at a two-year follow-up. This study revealed that the anti-saccade anticipatory responses decreased in amnestic MCI (aMCI). Correct vertical pro-saccades increased in non-amnestic MCI (naMCI), while the express saccades decreased. Our study demonstrated that longer than two years of follow-up is necessary to monitor the course of MCI. Findings of the relationships between longitudinal changes of saccades and cognitive measurements demonstrated the usability of eye movements in evaluating the process of MCI.