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© Research
Publication : BMC veterinary research

RACK1, a clue to the diagnosis of cutaneous melanomas in horses

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in BMC veterinary research - 29 Jun 2012

Campagne C, Julé S, Bernex F, Estrada M, Aubin-Houzelstein G, Panthier JJ, Egidy G

Link to Pubmed [PMID] – 22747534

BMC Vet. Res. 2012;8:95

Melanocytic proliferations are common in horses but the diagnosis of malignancy is not always straightforward. To improve diagnosis and prognosis, markers of malignancy are needed. Receptor for activated C kinase 1 (RACK1) protein may be such a marker. RACK1 was originally found to characterize malignant melanocytic lesions in the Melanoblastoma-bearing Libechov minipig (MeLiM) and, later, in human patients. Our purpose was to investigate the value of RACK1 in the classification of cutaneous melanocytic proliferations in horses.