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© Charles Dauguet
Virus VIH-1 (HIV-1), agent du sida, à la surface d'un lymphocyte. Image colorisée.
Publication : Retrovirology

Proteasome-independent degradation of HIV-1 in naturally non-permissive human placental trophoblast cells

Team: Group: MISTIC
Team: Archived: Regulation of Retroviral Infections
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Retrovirology - 15 May 2009

Ross AL, Cannou C, Barré-Sinoussi F, Menu E

Link to Pubmed [PMID] – 19445667

Retrovirology 2009;6:46

The human placenta-derived cell line BeWo has been demonstrated to be restrictive to cell-free HIV-1 infection. BeWo cells are however permissive to infection by VSV-G pseudotyped HIV-1, which enters cells by a receptor-independent mechanism, and to infection by HIV-1 via a cell-to-cell route.