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© Research
Publication : Emerging infectious diseases

Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic

Member: Brigitte Gicquel
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Emerging infectious diseases - 01 Sep 2006

Nouvel LX, Kassa-Kelembho E, Dos Vultos T, Zandanga G, Rauzier J, Lafoz C, Martin C, Blazquez J, Talarmin A, Gicquel B

Link to Pubmed [PMID] – 17073103

Emerging Infect. Dis. 2006 Sep;12(9):1454-6

We investigated multidrug-resistant (MDR) Mycobacterium tuberculosis strains in Bangui, Central African Republic. We found 39.6% with the same spoligotype and synonymous single nucleotide polymorphism in the mutT1 gene. However, strains had different rpoB mutations responsible for rifampin resistance. MDR strains in Bangui may emerge preferentially from a single, MDR-prone family.