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© Research
Publication : Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

HIV controllers: a homogeneous group of HIV-1-infected patients with spontaneous control of viral replication

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 30 Aug 2005

Lambotte O, Boufassa F, Madec Y, Nguyen A, Goujard C, Meyer L, Rouzioux C, Venet A, Delfraissy JF,

Link to Pubmed [PMID] – 16142675

Clin. Infect. Dis. 2005 Oct;41(7):1053-6

We identified a total 15 patients who have maintained undetectable plasma HIV RNA loads without antiretroviral treatment for >10 years from cohorts of 1300 and 1551 patients infected with human immunodeficiency virus (HIV). These 15 patients, whom we have referred to as “HIV controllers,” are characterized by a low HIV DNA load in peripheral blood mononuclear cells and by a strong HIV-specific immune response.