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© Research
Publication : Alcoholism, clinical and experimental research

Herpesvirus infection of the respiratory tract in patients with alcoholic hepatitis

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Alcoholism, clinical and experimental research - 01 Oct 1992

Pol S, Durand F, Bernuau J, Colin JF, Dubois F, Hautekeete M, Rouzioux C, Degott C, Rueff B, Benhamou JP

Link to Pubmed [PMID] – 1332527

Alcohol. Clin. Exp. Res. 1992 Oct;16(5):979-81

Respiratory herpesvirus infections have rarely been described in alcoholics. We report four cases of severe respiratory herpesvirus infections in patients with alcoholic liver disease. Two were related to Herpes Simplex Virus and two to Cytomegalovirus. Both chronic alcoholism and severe liver disease induce immunosuppression, which might account for these unusual herpesvirus infections of the respiratory tract. These cases suggest that infections with herpesviruses should be considered in patients with alcoholic liver disease and pulmonary or tracheobronchial disease unresponsive to standard antibiotic therapy. Bronchoscopy, viral culture, and serological tests appear warranted, particularly given the existence of specific therapy.