Evolution and diversity of clonal bacteria: the paradigm of Mycobacterium tuberculosis

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Deputy Director of Department
Deputy Director of National Reference Center
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Delivery of mengovirus-derived RNA replicons into tumoural liver enhances the anti-tumour efficacy of a peripheral peptide-based vaccine

Engineering attenuated virus vaccines by controlling replication fidelity

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Diseases

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Technique

Published in PloS one - 06 Feb 2008

Dos Vultos T, Mestre O, Rauzier J, Golec M, Rastogi N, Rasolofo V, Tonjum T, Sola C, Matic I, Gicquel B

Link to Pubmed [PMID] – 18253486

PLoS ONE 2008;3(2):e1538

Mycobacterium tuberculosis complex species display relatively static genomes and 99.9% nucleotide sequence identity. Studying the evolutionary history of such monomorphic bacteria is a difficult and challenging task.

Published on: 06 Feb 2008