Search anything and hit enter
  • Teams
  • Members
  • Projects
  • Events
  • Calls
  • Jobs
  • publications
  • Software
  • Tools
  • Network
  • Equipment

A little guide for advanced search:

  • Tip 1. You can use quotes "" to search for an exact expression.
    Example: "cell division"
  • Tip 2. You can use + symbol to restrict results containing all words.
    Example: +cell +stem
  • Tip 3. You can use + and - symbols to force inclusion or exclusion of specific words.
    Example: +cell -stem
e.g. searching for members in projects tagged cancer
Search for
Count
IN
OUT
Content 1
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Clinical Research Nurse
  • Clinician Researcher
  • Department Manager
  • Dual-education Student
  • Full Professor
  • Honorary Professor
  • Lab assistant
  • Master Student
  • Non-permanent Researcher
  • Nursing Staff
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Prize
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Content 2
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Clinical Research Nurse
  • Clinician Researcher
  • Department Manager
  • Dual-education Student
  • Full Professor
  • Honorary Professor
  • Lab assistant
  • Master Student
  • Non-permanent Researcher
  • Nursing Staff
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Prize
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Search

← Go to Research

Go back
Scroll to top
Share
© Research
Publication : American journal of respiratory and critical care medicine

Early Chest CT-Scan to Assist Diagnosis and Guide Treatment Decision for Suspected Community-Acquired Pneumonia

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in American journal of respiratory and critical care medicine - 13 Jul 2015

Claessens YE, Debray MP, Tubach F, Brun AL, Rammaert B, Hausfater P, Naccache JM, Ray P, Choquet C, Carette MF, Mayaud C, Leport C, Duval X

Link to Pubmed [PMID] – 26168322

Am. J. Respir. Crit. Care Med. 2015 Jul;

RATIONALE: Clinical decision making relative to community acquired-pneumonia CAP diagnosis is difficult. Chest X-ray is key in establishing parenchymal lung involvement. However, radiological performance may lead to misdiagnosis, rendering questionable the utility of chest CT-scan in patients with clinically-suspected CAP.

OBJECTIVE: To assess whether early multidetector chest CT-scan affects diagnosis and management of patients visiting the emergency department with suspected CAP.

METHODS: 319 prospectively enrolled patients with clinically suspected CAP patients underwent multidetector chest CT-scan within 4 hours. CAP diagnosis probability (definite, probable, possible or excluded), and therapeutic plans (antibiotic initiation/discontinuation, hospitalisation/discharge) were established by emergency physicians before and after CT scan results. The adjudication committee established the final CAP classification on day 28.

MEASUREMENTS AND MAIN RESULTS: Chest X-ray revealed a parenchymal infiltrate in 188 patients. CAP was initially classified as definite in 143 patients (44.8%), probable or possible in 172 (53.8%), excluded in 4 (1.2%). CT-scan revealed a parenchymal infiltrate in 40 (33%) of the patients without infiltrate on chest X-ray and excluded CAP in 56 (29.8%) of the 188 with parenchymal infiltrate on X-ray. CT-scan modified classification in 187 (58.6% 95%CI 53.2-64.0); leading to 50.8% definite CAP and 28.8% excluded CAP; 80% of modifications were in accordance with adjudication committee classification. Due to CT-scan, antibiotics were initiated in 51 (16%) and discontinued in 29 (9%), and hospitalisation was decided in 22 and discharge in 23.

CONCLUSIONS: In CAP-suspected patients visiting the emergency unit, early CT-scan findings complementary to chest X-ray markedly affect both diagnosis and clinical management. Clinical trial registration available at www.clinicaltrials.gov, ID NCT01574066.