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COVID-19-related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters.

Differential transcriptomic response of Anopheles arabiensis to Plasmodium vivax and Plasmodium falciparum infection

© Benoît Chassaing

Interaction microbiote-mucus à la surface de l’épithélium colique humain

Publication : American journal of physiology. Gastrointestinal and liver physiology

Dietary fat and low fiber in purified diets differently impact the gut-liver axis to promote obesity-linked metabolic impairments.

Team: Microbiome-Host Interactions

Team: U1306 – Host-Microbe interactions and pathophysiology

Member: Benoit Chassaing

Scientific Fields

Diseases

Organisms

Applications

Technique

Published in American journal of physiology. Gastrointestinal and liver physiology - 01 Jun 2021

Daniel N, Rossi Perazza L, Varin TV, Trottier J, Marcotte B, St-Pierre P, Barbier O, Chassaing B, Marette A

Link to Pubmed [PMID] – 33881354

Link to DOI – 10.1152/ajpgi.00028.2021

Am J Physiol Gastrointest Liver Physiol 2021 Jun; 320(6): G1014-G1033

Selecting the most relevant control diet is of critical importance for metabolic and intestinal studies in animal models. Chow and LF-purified diet differentially impact metabolic and gut microbiome outcomes resulting in major changes in intestinal integrity in LF-fed animals which contributes to altering metabolic homeostasis. Dietary fat and low fiber both contribute to the deleterious metabolic effect of purified HF diets through both selective and overlapping mechanisms.

Published on: 01 Jun 2021