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  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
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  • Deputy Director of National Reference Center
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  • Director of Center
  • Director of Department
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© Research
Publication : Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Cryptococcosis in solid organ transplant recipients: current state of the science

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Nov 2008

Singh N, Dromer F, Perfect JR, Lortholary O

Link to Pubmed [PMID] – 18840080

Clin. Infect. Dis. 2008 Nov;47(10):1321-7

Cryptococcosis remains a significant opportunistic infection in solid organ transplant recipients. Disease presentation and outcomes may be affected by, among other factors, the use of calcineurin inhibitor immunosuppressive agents. It is being increasingly recognized that rapid reversal of immunosuppression in transplant recipients treated for cryptococcosis incurs the risk of immune reconstitution inflammatory syndrome, which resembles worsening disease or relapse. This review summarizes the current state of knowledge regarding cryptococcosis in transplant recipients and highlights areas where future investigations are needed to further optimize outcomes for these patients.