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Deputy Director of National Reference Center
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Synthesis and enzymatic polymerisation of 5-amino-1-(2′-deoxy-beta-D-ribofuranosyl)imidazole-4-carboxamide-5′- triphosphate

V beta 17 gene polymorphism in wild-derived mouse strains: two amino acid substitutions in the V beta 17 region greatly alter T cell receptor specificity

© Perrine Bomme, Guillaume Duménil, Jean-Marc Panaud.

Coloured scanning electron micrograph (SEM) of Neisseria meningitidis on epithelial cells

Publication : Infection and immunity

Conservation of Neisseria gonorrhoeae pilus expression regulatory genes pilA and pilB in the genus Neisseria

Team: Invasive Bacterial Infections

Member: Muhamed-Kheir Taha

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Diseases

Organisms

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Technique

Published in Infection and immunity - 01 Dec 1990

Taha MK, Marchal C

Link to Pubmed [PMID] – 1979321

Infect. Immun. 1990 Dec;58(12):4145-8

The pili of Neisseria gonorrhoeae mediate bacterial adhesion to the host-susceptible tissues. We have previously reported the identification of two genes, pilA and pilB, which act in trans to regulate pilus expression. Besides this regulatory function, pilA participates in an essential function for bacterial viability. Here we show that pilA and pilB homologs are also present in a variety of other members of the Neisseriaceae family of bacteria in contrast to the gonococcal pilin gene which hybridizes only to the pathogenic Neisseria species.

Published on: 01 Dec 1990