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© Cédric Delevoye
Cellules infectÈes par Chlamydia trachomatis. Les bactÈries se dÈveloppent dans une vacuole (rouge), ‡ proximitÈ du noyau de la cellule-hÙte (bleu). Ce compartiment interagit de faÁon Ètroite avec ceux de la cellule hÙte. Marquage vert= localisation d'une protÈine de l'hÙte, Vamp8, exprimÈe par transfection. Les Chlamydia sont, selon les souches, responsables de maladies sexuellement transmises, de cÈcitÈs, d'infections pulmonaires et pourraient Ítre impliquÈes dans l'athÈrosclÈrose.
Publication : Current opinion in microbiology

Chlamydia: five years A.G. (after genome)

Team: Cellular Biology of Microbial Infection
Member: Agathe Subtil
Member: Alice Dautry
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Current opinion in microbiology - 01 Feb 2004

Subtil A, Dautry-Varsat A

Link to Pubmed [PMID] – 15036146

Curr. Opin. Microbiol. 2004 Feb;7(1):85-92

The obligate intracellular pathogens Chlamydiaceae are the agents of several human diseases. They cannot be genetically manipulated and they survive and replicate in a unique intracellular organelle called the inclusion. In the past five years, publications of the genome sequences of several strains have opened new areas of research. Some of these new advances are presented here.