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© Research
Publication : Parasitology today (Personal ed.)

Cell signalling and motility in Entamoeba histolytica

Member: Nancy Guillen
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Parasitology today (Personal ed.) - 01 Oct 1993

Guillén N

Link to Pubmed [PMID] – 15463670

Parasitol. Today (Regul. Ed.) 1993 Oct;9(10):364-9

Entamoeba histolytica crawls as a polarized cell following external stimuli, with the translocation of signals modifying extracellular matrix interactions and the amoeba cytoskeleton. Nancy Guillén here describes how the gliding of E. histolytica cells requires the activity of the actomyosin complex, and how actomyosin functions related to motility are necessary for pathogenesis and for amoebal escape from the host immune response.