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© Research
Publication : Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Bordetella pertussis and pertussis vaccines

Member: Nicole Guiso
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Nov 2009

Guiso N

Link to Pubmed [PMID] – 19839747

Clin. Infect. Dis. 2009 Nov;49(10):1565-9

Bordetella pertussis is a human-specific pathogen that causes whooping cough. The use of pertussis whole-cell vaccines in infants and toddlers led to decreased circulation of the bacterium in the child population and a marked decrease in the incidence of the disease. However, vaccine does not result in life-long immunity; indeed, the circulation of the bacterium has not been controlled in the adult population. Universal adult booster immunization is now possible using pertussis acellular vaccines, which target-and are thus likely to control-the virulence of this bacterium.