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© Valérie Zeitoun
Stéthoscope. Centre Médical de l'Institut Pasteur (CMIP).
Publication : Open forum infectious diseases

Absence of Macrolide-Resistant Mutations in Bordetella pertussis in Antananarivo (Madagascar) and Cambodia During the Last Pertussis Cycle Before the COVID-19 Pandemic.

Team: Medical Center of the Institut Pasteur
Member: Fabien Taieb
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Open forum infectious diseases - 01 Oct 2025

Campana F, Rajabizadeh M, Hide M, Delvallez G, Han S, Rafetrarivony L, Dim B, Harimanana A, Noel G, Ait-Ahmed M, Collard JM, Borand L, Guiso N, Taieb F

Link to Pubmed [PMID] – 41031104

Link to DOI – 10.1093/ofid/ofaf566

Open Forum Infect Dis 2025 Oct; 12(10): ofaf566

Macrolides are the first-line treatment against pertussis. The high prevalence of macrolide-resistant Bordetella pertussis (MRBP) strains reported in China is concerning. MBRP might be underestimated in other countries. Looking for the mutation causative for MRBP in retrospective studies conducted in Madagascar and Cambodia, we found no MRBP.