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© Ahmed Haouz
Cristaux d'une protéine de Mycobacterium tuberculosis produits dans le cadre du Grand Programme Horizontal sur la Tuberculose à l'Institut Pasteur. La caractérisation structurale de protéines mycobactériennes aide à une meilleure compréhension de la physiologie et de la pathogénicité des mycobactéries et fournit un point de départ pour la conception de nouveaux agents antibactériens.
Publication : European biophysics journal : EBJ

A plate holder for non-destructive testing of mesophase crystallization assays

Team: Crystallography
Member: Ariel Mechaly
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in European biophysics journal : EBJ - 11 Mar 2008

Agirre J, Mechaly A, Cabo-Bilbao A, Guérin DM

Link to Pubmed [PMID] – 18330553

Eur. Biophys. J. 2008 Jul;37(6):871-7

Here, we describe a goniometer holder to mount standard 96-well crystallization plates directly onto the goniometer head of an oscillation camera. This attachment was designed to check crystallization conditions straight from the crystallization plates under X-rays, and was proven to be useful for checking small crystals and solutions that destabilize monoolein-based lipidic cubic phase (LCP) crystallization experiments. A quick procedure for setting up LCP assays employing commercially available instruments is also reported.