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© Research
Publication : International journal of environmental research and public health

A Cross-Sectional Study of Exposure Factors Associated with Seropositivity for SARS-CoV-2 Antibodies during the Second Epidemic Wave among a Sample of the University of Corsica (France).

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in International journal of environmental research and public health - 10 Feb 2022

Decarreaux D, Sevila J, Masse S, Capai L, Fourié T, Saba Villarroel PM, Amroun A, Nurtop E, Vareille M, Pouquet M, Blanchon T, de Lamballerie X, Charrel R, Falchi A

Link to Pubmed [PMID] – 35206161

Link to DOI – 10.3390/ijerph19041953

Int J Environ Res Public Health 2022 Feb; 19(4):

This study aimed to estimate the seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection within the staff and student populations of the University of Corsica (France) during the second wave of the epidemic.A cross-sectional survey was conducted from 23 November 2020 to 31 January 2021. The participants underwent blood sampling using a fingerstick procedure and completed an anonymized questionnaire. Sera were tested for the presence of anti-SARS-CoV-2 IgG (ELISA-S) and, if positive, with an in-house virus neutralization test (VNT).A total of 418 persons were included in the study. The overall seroprevalence was 12.8% (95% confidence interval (CI), 9.8-16.6%). A total of 15 (31%) of the 49 individuals who had a positive ELISA-S also had a positive VNT. Seropositivity was associated with living at the city campus during the week and on weekends (OR = 3.74 [1.40-12.00]), using public transportation/carpooling (OR = 2.00 [1.01-4.02]), and being in contact with a person who tested positive for SARS-CoV-2 (OR = 2.32 [1.20-4.40]). The main symptoms associated with seropositivity were “having had an acute respiratory infection” (OR = 3.05 [1.43-6.43]) and “experiencing loss of smell” (OR = 16.4 [5.87-50.7]).These results could be useful for SARS-CoV-2 prevention and control on university campuses.