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Guides
  • 2025
    Vertti-Quintero N, Delahousse C, Aristov A, Traboulsi T, Cossec JC, Baroud CN, Sart S, Culture of pluripotent stem cells in microscale droplets modulates differentiation and tissue patterning towards organoids on chip., Stem Cell Res Ther 2025 Sep; 16(1): 510.
  • 2025
    Goffeney A, Hendriks IA, Morel V, Loe-Mie Y, Charon F, Nielsen ML, Cossec JC, Noordermeer D, Seeler JS, Dejean A, SUMO operates from a unique long tandem repeat to keep innate immunity in check., Nucleic Acids Res 2025 Jul; 53(14): .
  • 2025
    Mata-Garrido J, Zafferri I, Nordlinger A, Loe-Mie Y, Dejean A, Cossec JC, Transient pharmacological inhibition of SUMOylation during pregnancy induces craniofacial malformations in offspring mice., Eur J Cell Biol 2025 Jun; 104(2): 151480.
  • 2023
    Traboulsi T, Sart S, Baroud CN, Dejean A, Cossec JC, Generation of embryo-like structures from mouse embryonic stem cells treated with a chemical inhibitor of SUMOylation and cultured in microdroplets., STAR Protoc 2023 Dec; 4(4): 102573.
  • 2023
    Cossec JC, Traboulsi T, Sart S, Loe-Mie Y, Guthmann M, Hendriks IA, Theurillat I, Nielsen ML, Torres-Padilla ME, Baroud CN, Dejean A, Transient suppression of SUMOylation in embryonic stem cells generates embryo-like structures., Cell Rep 2023 Apr; 42(4): 112380.
  • 2020
    Theurillat I, Hendriks IA, Cossec JC, Andrieux A, Nielsen ML, Dejean A, Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic Cells., Cell Rep 2020 Oct; 33(1): 108251.
  • 2020
    Theurillat I, Hendriks IA, Cossec JC, Andrieux A, Nielsen ML, Dejean A, Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic Cells., Cell Rep 2020 Sep; 32(11): 108146.
  • 2020
    Botté A, Lainé J, Xicota L, Heiligenstein X, Fontaine G, Kasri A, Rivals I, Goh P, Faklaris O, Cossec JC, Morel E, Rebillat AS, Nizetic D, Raposo G, Potier MC, Ultrastructural and dynamic studies of the endosomal compartment in Down syndrome., Acta Neuropathol Commun 2020 Jun; 8(1): 89.
  • 2018
    Cossec JC, Theurillat I, Chica C, Búa Aguín S, Gaume X, Andrieux A, Iturbide A, Jouvion G, Li H, Bossis G, Seeler JS, Torres-Padilla ME, Dejean A, SUMO Safeguards Somatic and Pluripotent Cell Identities by Enforcing Distinct Chromatin States., Cell Stem Cell 2018 Nov; 23(5): 742-757.e8.
  • 2018
    Cossec JC*, Theurillat I*, Chica C, Bua Aguin S, Gaume X, Andrieux A, Iturbide A, Jouvion G, Li H, Bossis G, Seeler J-S, Torres-Padilla ME, Dejean A, SUMO safeguards somatic and pluripotent cell identities by enforcing distinct chromatin states, Cell Stem Cell. 2018 Nov 1;23(5):742-757.e8. doi: 10.1016/j.stem.2018.10.001.
  • 2015
    Decque A, Joffre O, Magalhaes JG, Cossec JC, Blecher-Gonen R, Lapaquette P, Silvin A, Manel N, Joubert PE, Seeler JS, Albert ML, Amit I, Amigorena S, Dejean A, Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing., Nat Immunol 2016 Feb; 17(2): 140-9.
  • 2015
    Corlier F, Rivals I, Lagarde J, Hamelin L, Corne H, Dauphinot L, Ando K, Cossec JC, Fontaine G, Dorothée G, Malaplate-Armand C, Olivier JL, Dubois B, Bottlaender M, Duyckaerts C, Sarazin M, Potier MC, Modifications of the endosomal compartment in peripheral blood mononuclear cells and fibroblasts from Alzheimer’s disease patients., Transl Psychiatry 2015 Jul; 5(7): e595.
  • 2013
    Neyret-Kahn H, Benhamed M, Ye T, Le Gras S, Cossec JC, Lapaquette P, Bischof O, Ouspenskaia M, Dasso M, Seeler J, Davidson I, Dejean A, Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation., Genome Res 2013 Oct; 23(10): 1563-79.
  • 2012
    Cossec JC, Lavaur J, Berman DE, Rivals I, Hoischen A, Stora S, Ripoll C, Mircher C, Grattau Y, Olivomarin JC, de Chaumont F, Lecourtois M, Antonarakis SE, Veltman JA, Delabar JM, Duyckaerts C, Di Paolo G, Potier MC, Trisomy for synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes., Hum Mol Genet 2012 Jul; 21(14): 3156-72.
  • 2012
    Devauges V, Marquer C, Lécart S, Cossec JC, Potier MC, Fort E, Suhling K, Lévêque-Fort S, Homodimerization of amyloid precursor protein at the plasma membrane: a homoFRET study by time-resolved fluorescence anisotropy imaging., PLoS One 2012 ; 7(9): e44434.
  • 2011
    Marquer C, Devauges V, Cossec JC, Liot G, Lécart S, Saudou F, Duyckaerts C, Lévêque-Fort S, Potier MC, Local cholesterol increase triggers amyloid precursor protein-Bace1 clustering in lipid rafts and rapid endocytosis., FASEB J 2011 Apr; 25(4): 1295-305.
  • 2010
    Cossec JC, Simon A, Marquer C, Moldrich RX, Leterrier C, Rossier J, Duyckaerts C, Lenkei Z, Potier MC, Clathrin-dependent APP endocytosis and Abeta secretion are highly sensitive to the level of plasma membrane cholesterol., Biochim Biophys Acta 2010 Aug; 1801(8): 846-52.
  • 2010
    Cossec JC, Marquer C, Panchal M, Lazar AN, Duyckaerts C, Potier MC, Cholesterol changes in Alzheimer’s disease: methods of analysis and impact on the formation of enlarged endosomes., Biochim Biophys Acta 2010 Aug; 1801(8): 839-45.
  • 2010
    Panchal M, Loeper J, Cossec JC, Perruchini C, Lazar A, Pompon D, Duyckaerts C, Enrichment of cholesterol in microdissected Alzheimer’s disease senile plaques as assessed by mass spectrometry., J Lipid Res 2010 Mar; 51(3): 598-605.
  • 2009
    Blandin P, Lévêque-Fort S, Lécart S, Cossec JC, Potier MC, Lenkei Z, Druon F, Georges P, Time-gated total internal reflection fluorescence microscopy with a supercontinuum excitation source., Appl Opt 2009 Jan; 48(3): 553-9.
  • 2006
    Senée V, Chelala C, Duchatelet S, Feng D, Blanc H, Cossec JC, Charon C, Nicolino M, Boileau P, Cavener DR, Bougnères P, Taha D, Julier C, Mutations in GLIS3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism., Nat Genet 2006 Jun; 38(6): 682-7.
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