• 2025
  Pierre Authié, Philippe Souque, Fanny Moncoq, Amandine Noirat, Catherine Blanc, Sylvain Ciret, Maryline Bourgine, David Hardy, Françoise Guinet, Laleh Majlessi, Pierre Charneau, Kirill Nemirov, Lentiviral vector-based T-cell vaccines against Zika and yellow fever viruses, Vaccine.
• 2025
  Coleon A, Larrous F, Kergoat L, Tichit M, Hardy D, Obadia T, Kornobis E, Bourhy H, de Melo GD, Hamsters with long COVID present distinct transcriptomic profiles associated with neurodegenerative processes in brainstem, Nat Commun 2025 Jul; 16(1): 6714.
• 2025
  Flavio Alvarez, Guilherme Dias de Melo, Florence Larrous, Lauriane Kergoat, Batiste Boëda, Vincent Michel, Danielle Seilhean, Magali Tichit, David Hing, David Hardy, Etienne Kornobis, Hervé Bourhy, Nicolas Wolff, Célia Caillet-Saguy, The SARS-CoV-2 envelope PDZ binding motif acts as a virulence factor disrupting host’s epithelial cell–cell junctions [brief report], Cellular and Molecular Biology Letters, 2025, 30 (1), pp.80. ⟨10.1186/s11658-025-00758-y⟩.
• 2025
  Vincent Legros, Essia Belarbi, Patricia Jeannin, Virginie Geolier, Beate Kümmerer, David Hardy, Philippe Desprès, Antoine Gessain, Pierre Roques, Pierre-Emmanuel Ceccaldi, Valérie Choumet, Use of Recombinant Chikungunya Virus expressing Nanoluciferase to Identify Chondrocytes as Target Cells in an Immunocompetent Mouse Model, Journal of Infectious Diseases, In press, pp.jiaf232. ⟨10.1093/infdis/jiaf232⟩.
• 2025
  Papadopoulos S, Hardy D, Vernel-Pauillac F, Tichit M, Boneca IG, Werts C, Myocarditis and neutrophil-mediated vascular leakage but not cytokine storm associated with fatal murine leptospirosis., EBioMedicine 2025 Jan; 112(): 105571.
• 2024
  Beretta M, Vesin B, Wei Y, Planchais C, Rosenbaum P, Ait-Goughoulte M, Pelletier N, Hardy D, Mouquet H, Bourgine M, Enhanced hepatitis B virus-specific immunity by combining neutralizing antibody therapy and DNA vaccination in a murine model of chronic hepatitis B virus infection., Hepatology 2024 Dec; (): .
• 2024
  Hamelin B, Pérot P, Pichler I, Haslbauer JD, Hardy D, Hing D, Loulizi S, Regnault B, Pieters A, Heijnen I, Berkemeier C, Mancuso M, Kufner V, Willi N, Jamet A, Dheilly N, Eloit M, Recher M, Huber M, Mertz KD, Circovirus Hepatitis in Immunocompromised Patient, Switzerland., Emerg Infect Dis 2024 Oct; 30(10): 2140-2144.
• 2024
  Abdoulaye Sissoko, Astan Cissé, Clémence Duverdier, Mickaël Marin, Lucie Dumas, Sandra Manceau, Blandine Maître, Anita Eckly, Aurélie Fricot-Monsinjon, Camille Roussel, Papa Alioune Ndour, Michael Dussiot, Safi Dokmak, Béatrice Aussilhou, Jeanne Dembinski, Alain Sauvanet, François Paye, Mickaël Lesurtel, Jérôme Cros, Dominique Wendum, Magali Tichit, David Hardy, Carmen Capito, Slimane Allali, Pierre Buffet, Clearance of pathogenic erythrocytes is maintained despite spleen dysfunction in children with sickle cell disease, Am J Hematol.
• 2024
  Alseny M'mah Soumah, Mariame Camara, Justin Windingoudi Kaboré, Ibrahim Sadissou, Hamidou Ilboudo, Christelle Travaillé, Oumou Camara, Magali Tichit, Jacques Kaboré, Salimatou Boiro, Aline Crouzols, Jean Marc Tsagmo Ngoune, David Hardy, Aïssata Camara, Vincent Jamonneau, Annette MacLeod, Jean-Mathieu Bart, Mamadou Camara, Bruno Bucheton, Brice Rotureau, Prevalence of dermal trypanosomes in suspected and confirmed cases of gambiense human African trypanosomiasis in Guinea, 2024 Aug 19;18(8):e0012436..
• 2024
  Fefeu M, Blatzer M, Kneppers A, Briand D, Rocheteau P, Haroche A, Hardy D, Juchet-Martin M, Danckaert A, Coudoré F, Tutakhail A, Huchet C, Lafoux A, Mounier R, Mir O, Gaillard R, Chrétien F, Serotonin reuptake inhibitors improve muscle stem cell function and muscle regeneration in male mice., Nat Commun 2024 Jul; 15(1): 6457.
• 2024
  Brunet J, Choucha Z, Gransagne M, Tabbal H, Ku M-W, Buchrieser J, Fernandes P, Batalie D, Lopez J, Ma L, Dufour E, Simon E, Hardy D, Petres S, Guinet F, Strick-Marchand H, Monot M, Charneau P, Majlessi L, Duprex WP, Gerke C, Martin A, Escriou N, A measles-vectored vaccine candidate expressing prefusion-stabilized SARS-CoV-2 spike protein brought to phase I/II clinical trials: candidate selection in a preclinical murine model., J Virol 2024 Apr; (): e0169323.
• 2024
  Maure A, Lawarée E, Fiorentino F, Pawlik A, Gona S, Giraud-Gatineau A, Eldridge MJG, Danckaert A, Hardy D, Frigui W, Keck C, Gutierrez C, Neyrolles O, Aulner N, Mai A, Hamon M, Barreiro LB, Brodin P, Brosch R, Rotili D, Tailleux L, A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection., PLoS Biol 2024 Apr; 22(4): e3002259.
• 2023
  Steven Kho, Nurjati C Siregar, Labibah Qotrunnada, Aurélie Fricot, Abdoulaye Sissoko, Putu A I Shanti, Freis Candrawati, Noy N Kambuaya, Hasrini Rini, Benediktus Andries, David Hardy, Nur I Margyaningsih, Fauziyah Fadllan, Desandra A Rahmayenti, Agatha M Puspitasari, Leo Leonardo, Bagus T G Yayang, Dewi S Margayani, Pak Prayoga, Leily Trianty, Enny Kenangalem, Ric N Price, Tsin W Yeo, Gabriela Minigo, Rintis Noviyanti, Jeanne R Poespoprodjo, Nicholas M Anstey, Pierre A Buffet, Retention of uninfected red blood cells causing congestive splenomegaly is the major mechanism of anemia in malaria, Am J Hematol.
• 2023
  Alexis Lamiable, Tiphaine Champetier, Francesco Leonardi, Ethan Cohen, Peter Sommer, David Hardy, Nicolas Argy, Achille Massougbodji, Elaine Del Nery, Gilles Cottrell, Yong-Jun Kwon & Auguste Genovesio , Revealing invisible cell phenotypes with conditional generative modeling, Nature Communications 6386 (2023).
• 2023
  Douguet L, Fert I, Lopez J, Vesin B, Le Chevalier F, Moncoq F, Authié P, Nguyen TM, Noirat A, Névo F, Blanc C, Bourgine M, Hardy D, Anna F, Majlessi L, Charneau P, Full eradication of pre-clinical human papilloma virus-induced tumors by a lentiviral vaccine., EMBO Mol Med 2023 Sep; (): e17723.
• 2023
  Eugenie Melaine Kemta Magang, Rolin Mitterran Ndefo Kamga, Jenny Telleria, Magali Tichit, Aline Crouzols, Jacques Kaboré, David Hardy, Calmes Ursain Tsakeng Bouaka, Vincent Jamonneau, Brice Rotureau, Victor Kuete, Jean-Mathieu Bart, Gustave Simo, Prevalence of blood and skin trypanosomes in domestic and wild fauna from two sleeping sickness foci in Southern Cameroon, PLOS Neglected Tropical Diseases.
• 2023
  de Melo GD, Perraud V, Alvarez F, Vieites-Prado A, Kim S, Kergoat L, Coleon A, Trüeb BS, Tichit M, Piazza A, Thierry A, Hardy D, Wolff N, Munier S, Koszul R, Simon-Lorière E, Thiel V, Lecuit M, Lledo PM, Renier N, Larrous F, Bourhy H, Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants., Nat Commun 2023 Jul; 14(1): 4485.
• 2023
  Le Chevalier F, Authié P, Chardenoux S, Bourgine M, Vesin B, Cussigh D, Sassier Y, Fert I, Noirat A, Nemirov K, Anna F, Bérard M, Guinet F, Hardy D, Charneau P, Lemonnier F, Langa-Vives F, Majlessi L, Mice humanized for MHC and hACE2 with high permissiveness to SARS-CoV-2 omicron replication., Microbes Infect 2023 ; 25(7): 105142.
• 2022
  Benjamin Vesin 1 , Pierre Authié 1 , Catherine Blanc 1 , Ingrid Fert 1 , Amandine Noirat 1 , Fabien Le Chevalier 1 , Yu Wei 1 , Min-Wen Ku 1 , Kirill Nemirov 1 , François Anna 1 , David Hardy 2 , Cyril Planchais 3 , Hugo Mouquet 3 , Françoise Guinet 4 , Pierre Charneau 1 , Laleh Majlessi 1 , Maryline Bourgine 1, Full-Lung Prophylaxis against SARS-CoV-2 by One-Shot or Booster Intranasal Lentiviral Vaccination in Syrian Golden Hamsters, Vaccines (Basel).
• 2022
  Anna F, Lopez J, Moncoq F, Blanc C, Authié P, Noirat A, Fert I, Souque P, Nevo F, Pawlik A, Hardy D, Goyard S, Hudrisier D, Brosch R, Guinet F, Neyrolles O, Charneau P, Majlessi L, , A lentiviral vector expressing a dendritic cell-targeting multimer induces mucosal anti-mycobacterial CD4+ T-cell immunity., Mucosal Immunol 2022 Sep; (): .
• 2022
  Abdoulaye Sissoko, Aurélie Fricot-Monsinjon, Camille Roussel, Sandra Manceau, Lucie Dumas, Carmen Capito, Slimane Allali, Narjis Yekkache, Michael Dussiot, Yann Nguyen, Agnès Lefort Des Ylouses, Béatrice Aussilhou, Magali Tichit, David Hardy, Blandine Maître, Anita Eckly, Mariane De Montalembert, Marina Cavazzana, Laure Joseph, Pierre Buffet, Erythrocytic vacuoles that accumulate a fluorescent dye predict spleen size and function in sickle cell disease, American Journal of Hematology.
• 2022
  Lopez J, Anna F, Authié P, Pawlik A, Ku MW, Blanc C, Souque P, Moncoq F, Noirat A, Hardy D, Sougakoff W, Brosch R, Guinet F, Charneau P, Majlessi L, , A lentiviral vector encoding fusion of light invariant chain and mycobacterial antigens induces protective CD4+ T cell immunity., Cell Rep 2022 Jul; 40(4): 111142.
• 2022
  Benoît Henry, Geoffroy Volle, Hilaire Akpovi, Laure Gineau, Camille Roussel, Papa Alioune Ndour, Félicien Tossou, Felipe Suarez, Friso Palstra, Aurélie Fricot, Charlotte Chambrion, Julien Solinc, Julie Nguyen, Mathilde Garé, Florentin Aussenac, Charles-Henry Cottart, Christine Keyser, Rafiou Adamou, Magali Tichit, David Hardy, Nadine Fievet, Jérôme Clain, André Garcia, David Courtin, Olivier Hermine, Audrey Sabbagh, Pierre Buffet, Splenic clearance of rigid erythrocytes as an inherited mechanism for splenomegaly and natural resistance to malaria, EBio Medicine.
• 2022
  Vesin B, Lopez J, Noirat A, Authié P, Fert I, Le Chevalier F, Moncoq F, Nemirov K, Blanc C, Planchais C, Mouquet H, Guinet F, Hardy D, Vives FL, Gerke C, Anna F, Bourgine M, Majlessi L, Charneau P, , An intranasal lentiviral booster reinforces the waning mRNA vaccine-induced SARS-CoV-2 immunity that it targets to lung mucosa., Mol Ther 2022 Apr; (): .
• 2021
  Ku MW, Authié P, Bourgine M, Anna F, Noirat A, Moncoq F, Vesin B, Nevo F, Lopez J, Souque P, Blanc C, Fert I, Chardenoux S, Lafosse L, Cussigh D, Hardy D, Nemirov K, Guinet F, Langa Vives F, Majlessi L, Charneau P, , Brain cross-protection against SARS-CoV-2 variants by a lentiviral vaccine in new transgenic mice., EMBO Mol Med 2021 12; 13(12): e14459.
• 2021
  Frantz PN, Barinov A, Ruffié C, Combredet C, Najburg V, de Melo GD, Larrous F, Kergoat L, Teeravechyan S, Jongkaewwattana A, Billon-Denis E, Tournier JN, Prot M, Levillayer L, Conquet L, Montagutelli X, Tichit M, Hardy D, Fernandes P, Strick-Marchand H, Di Santo J, Simon-Lorière E, Bourhy H, Tangy F, A live measles-vectored COVID-19 vaccine induces strong immunity and protection from SARS-CoV-2 challenge in mice and hamsters., Nat Commun 2021 Nov; 12(1): 6277.
• 2021
  de Melo GD, Lazarini F, Larrous F, Feige L, Kornobis E, Levallois S, Marchio A, Kergoat L, Hardy D, Cokelaer T, Pineau P, Lecuit M, Lledo PM, Changeux JP, Bourhy H, , Attenuation of clinical and immunological outcomes during SARS-CoV-2 infection by ivermectin., EMBO Mol Med 2021 Aug; 13(8): e14122.
• 2021
  Kho S, Qotrunnada L, Leonardo L, Andries B, Wardani P, Fricot A, Henry B, Hardy D, Margyaningsih N, Apriyanti D, Puspitasari A, Prayoga P, Trianty L, Kenangalem E, Chretien F, Safeukui I, Del Portillo H, Fernandez-Becerra C, Meibalan E, Marti M, N Price R, Woodberry T, Ndour P, Russell B, W Yeo T, Minigo G, Noviyanti R, Poespoprodjo J, Siregar N, Buffet P, Anstey N, Hidden Biomass of Intact Malaria Parasites in the Human Spleen, N Engl J Med 2021; 384:2067-2069.
• 2021
  Kho S, Qotrunnada L, Leonardo L, Andries B, Wardani P, Fricot A, Henry B, Hardy D, Margyaningsih N, Apriyanti D, Puspitasari A, Prayoga P, Trianty L, Kenangalem E, Chretien F, Safeukui I, Del Portillo H, Fernandez-Becerra C, Meibalan E, Marti M, N Price R, Woodberry T, Ndour P, Russell B, W Yeo T, Minigo G, Noviyanti R, Poespoprodjo J, Siregar N, Buffet P, Anstey N, Evaluation of splenic accumulation and colocalization of immature reticulocytes and Plasmodium vivax in asymptomatic malaria: A prospective human splenectomy study, PLoS Med . 2021 May 26;18(5):e1003632.
• 2021
  Conde E, Bertrand R, Balbino B, Bonnefoy J, Stackowicz J, Caillot N, Colaone F, Hamdi S, Houmadi R, Loste A, Kamphuis JBJ, Huetz F, Guilleminault L, Gaudenzio N, Mougel A, Hardy D, Snouwaert JN, Koller BH, Serra V, Bruhns P, Grouard-Vogel G, Reber LL, , Dual vaccination against IL-4 and IL-13 protects against chronic allergic asthma in mice., Nat Commun 2021 May; 12(1): 2574.
• 2020
  Ku MW, Bourgine M, Authié P, Lopez J, Nemirov K, Moncoq F, Noirat A, Vesin B, Nevo F, Blanc C, Souque P, Tabbal H, Simon E, Hardy D, Le Dudal M, Guinet F, Fiette L, Mouquet H, Anna F, Martin A, Escriou N, Majlessi L, Charneau P, , Intranasal vaccination with a lentiviral vector protects against SARS-CoV-2 in preclinical animal models., Cell Host Microbe 2021 Feb 10;29(2):236-249: .
• 2020
  Charlotte Lamirault , Elise Brisebard , Annalisa Patriarca , Marjorie Juchaux , Delphine Crepin , Dalila Labiod , Frederic Pouzoulet , Catherine Sebrie , Laurene Jourdain , Marine Le Dudal , David Hardy , Ludovic de Marzi , Remi Dendale , Gregory Jouvion , Yolanda Prezado , Spatially Modulated Proton Minibeams Results in the Same Increase of Lifespan as a Uniform Target Dose Coverage in F98-Glioma-Bearing Rats, Radiat Research.
• 2020
  Charlotte Lamirault, Valérie Doyère, Marjorie Juchaux, Frederic Pouzoulet, Dalila Labiod, Remi Dendale, Annalisa Patriarca, Catherine Nauraye, Marine Le Dudal, Grégory Jouvion, David Hardy, Nicole El Massioui, Yolanda Prezado, Short and long-term evaluation of the impact of proton minibeam radiation therapy on motor, emotional and cognitive functions, Sci Rep . 2020 Aug 11;10(1):13511.
• 2020
  Aguilar-Rojas A, Castellanos-Castro S, Matondo M, Gianetto QG, Varet H, Sismeiro O, Legendre R, Fernandes J, Hardy D, Coppée JY, Olivo-Marin JC, Guillen N, , Insights into amebiasis using a human 3D-intestinal model., Cell Microbiol 2020 Aug; 22(8): e13203.
• 2020
  Silvia Castellanos-Castro, Arturo Aguilar-Rojas, Mariette Matondo, Quentin Gian Gianetto, Hugo Varet, Odile Sismeiro, Rachel Legendre, Julien Fernandes, David Hardy, Jean Yves Coppée, Jean Christophe Olivo-Marin, Nancy Guillen, Human Immune Response Triggered by Entamoeba histolytica in a 3D-Intestinal Model, Eukaryome Impact on Human Intestine Homeostasis and Mucosal Immunology. Springer, Cham.
• 2020
  Bottai D, Frigui W, Sayes F, Di Luca M, Spadoni D, Pawlik A, Zoppo M, Orgeur M, Khanna V, Hardy D, Mangenot S, Barbe V, Medigue C, Ma L, Bouchier C, Tavanti A, Larrouy-Maumus G, Brosch R, TbD1 deletion as a driver of the evolutionary success of modern epidemic Mycobacterium tuberculosis lineages, Nat Commun 2020 Feb;11(1):684.
• 2020
  Manet C, Simon-Lorière E, Jouvion G, Hardy D, Prot M, Conquet L, Flamand M, Panthier JJ, Sakuntabhai A, Montagutelli X, , Genetic Diversity of Collaborative Cross Mice Controls Viral Replication, Clinical Severity, and Brain Pathology Induced by Zika Virus Infection, Independently of Oas1b., J Virol 2020 01; 94(3): .
• 2019
  Lee CH, Kang TH, Godon O, Watanabe M, Delidakis G, Gillis CM, Sterlin D, Hardy D, Cogné M, Macdonald LE, Murphy AJ, Tu N, Lee J, McDaniel JR, Makowski E, Tessier PM, Meyer AS, Bruhns P, Georgiou G, An engineered human Fc domain that behaves like a pH-toggle switch for ultra-long circulation persistence, Nat. Commun. 10, 5031..
• 2019
  Hardy D, Fefeu M, Besnard A, Briand D, Gasse P, Arenzana-Seisdedos F, Rocheteau P & Chrétien F, Defective angiogenesis in CXCL12 mutant mice impairs skeletal muscle regeneration, https://skeletalmusclejournal.biomedcentral.com/articles/10.1186/s13395-019-0210-5.
• 2019
  Bouglé A, Rocheteau P, Briand D, Hardy D, Verdonk F, Tremolada C, Hivelin M, Chretien F, Beneficial role of adipose-derived mesenchymal stem cells from micro-fragmented fat in a murine model of Duchenne Muscular Dystrophy., Muscle Nerve. 2019 Jun 22. doi: 10.1002/mus.26614.
• 2018
  Mayeuf-Louchart A, Hardy D, Thorel Q, Roux P, Gueniot L, Briand D, Mazeraud A, Bouglé A, Shorte SL, Staels B, Chrétien F, Duez H, Danckaert A, MuscleJ: a high-content analysis method to study skeletal muscle with a new Fiji tool, Skelet Muscle 2018 Aug;8(1):25.
• 2017
  Prezado Y, Jouvion G, Hardy D, Patriarca A, Nauraye C, Bergs J, González W, Guardiola C, Juchaux M, Labiod D, Dendale R, Jourdain L, Sebrie C, Pouzoulet F, Proton minibeam radiation therapy spares normal rat brain: Long-Term Clinical, Radiological and Histopathological Analysis, Sci Rep 2017 Oct;7(1):14403.
• 2016
  Hardy D, Besnard A, Latil M, Jouvion G, Briand D, Thépenier C, Pascal Q, Guguin A, Gayraud-Morel B, Cavaillon JM, Tajbakhsh S, Rocheteau P, Chrétien F, Comparative Study of Injury Models for Studying Muscle Regeneration in Mice, PLoS ONE 2016;11(1):e0147198.