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Guides
  • 2025
    Bonnet I, Orgeur M, Brossier F, Sayes F, Frigui W, Madacki J, Varet H, Chauffour A, Aubry A, Veziris N, Sougakoff W, Brosch R, Tournebize R, Evaluation of the role of whiB6 and kdpDE in the dominant multidrug-resistant clone Mycobacterium tuberculosis B0/W148., Microbiol Spectr 2025 May; (): e0322424.
  • 2025
    Touré H, Durand N, Orgeur M, Galindo LA, Girard-Misguich F, Guénal I, Herrmann JL, Szuplewski S, ENaC is a host susceptibility factor to bacterial infections in cystic fibrosis context., Commun Biol 2025 Apr; 8(1): 653.
  • 2024
    Vallecillo-García P, Kühnlein MN, Orgeur M, Hansmeier NR, Kotsaris G, Meisen ZG, Timmermann B, Giesecke-Thiel C, Hägerling R, Stricker S, Mesenchymal Osr1+ cells regulate embryonic lymphatic vessel formation., Development 2024 Sep; 151(17): .
  • 2023
    Vallecillo-García P, Orgeur M, Comai G, Poehle-Kronawitter S, Fischer C, Gloger M, Dumas CE, Giesecke-Thiel C, Sauer S, Tajbakhsh S, Höpken UE, Stricker S, A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation., Immunity 2023 Jun; 56(6): 1204-1219.e8.
  • 2021
    Jan Madacki, Mickael Orgeur, Guillem Mas Fiol, Wafa Frigui, Laurence Ma, Roland Brosch, ESX-1-Independent Horizontal Gene Transfer by Mycobacterium tuberculosis Complex Strains, mBio, 2021, 12 (3), ⟨10.1128/mBio.00965-21⟩.
  • 2021
    Orgeur M, Frigui W, Pawlik A, Clark S, Williams A, Ates LS, Ma L, Bouchier C, Parkhill J, Brodin P, Brosch R, , Pathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts., Microb Genom 2021 02; 7(2): .
  • 2020
    Bottai D, Frigui W, Sayes F, Di Luca M, Spadoni D, Pawlik A, Zoppo M, Orgeur M, Khanna V, Hardy D, Mangenot S, Barbe V, Medigue C, Ma L, Bouchier C, Tavanti A, Larrouy-Maumus G, Brosch R, TbD1 deletion as a driver of the evolutionary success of modern epidemic Mycobacterium tuberculosis lineages, Nat Commun 2020 Feb;11(1):684.
  • 2018
    Sayes F, Blanc C, Ates LS, Deboosere N, Orgeur M, Le Chevalier F, Gröschel MI, Frigui W, Song OR, Lo-Man R, Brossier F, Sougakoff W, Bottai D, Brodin P, Charneau P, Brosch R, Majlessi L, Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors, Cell Rep 2018 Apr;23(4):1072-1084.
  • 2017
    Orgeur M, Brosch R, Evolution of virulence in the Mycobacterium tuberculosis complex, Curr. Opin. Microbiol. 2017 Dec;41:68-75.
  • 2017
    Gröschel MI, Sayes F, Shin SJ, Frigui W, Pawlik A, Orgeur M, Canetti R, Honoré N, Simeone R, van der Werf TS, Bitter W, Cho SN, Majlessi L, Brosch R,, Recombinant BCG Expressing ESX-1 of Mycobacterium marinum Combines Low Virulence with Cytosolic Immune Signaling and Improved TB Protection, Cell Reports 2017, 18, (11), 2752–2765.
  • 2016
    Sapriel G, Konjek J, Orgeur M, Bouri L, Frézal L, Roux AL, Dumas E, Brosch R, Bouchier C, Brisse S, Vandenbogaert M, Thiberge JM, Caro V, Ngeow YF, Tan JL, Herrmann JL, Gaillard JL, Heym B, Wirth T, Genome-wide mosaicism within Mycobacterium abscessus: evolutionary and epidemiological implications., BMC Genomics 2016 Feb; 17(): 118.
  • 2016
    Eva C. Boritsch, Wafa Frigui, Alessandro Cascioferro, Wladimir Malaga, Gilles Etienne, Françoise Laval, Alexandre Pawlik, Fabien Le Chevalier, Mickael Orgeur, Laurence Ma, Christiane Bouchier, Timothy P. Stinear, Philip Supply, Laleh Majlessi, Mamadou Daffé, Christophe Guilhot & Roland Brosch, pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence, Nature Microbiol. 1, 15019 (2016).
  • 2013
    Supply P, Marceau M, Mangenot S, Roche D, Rouanet C, Khanna V, Majlessi L, Criscuolo A, Tap J, Pawlik A, Fiette L, Orgeur M, Fabre M, Parmentier C, Frigui W, Simeone R, Boritsch EC, Debrie AS, Willery E, Walker D, Quail MA, Ma L, Bouchier C, Salvignol G, Sayes F, Cascioferro A, Seemann T, Barbe V, Locht C, Gutierrez MC, Leclerc C, Bentley SD, Stinear TP, Brisse S, Médigue C, Parkhill J, Cruveiller S, Brosch R, Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis, Nat. Genet. 2013 Feb;45(2):172-9.
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