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© Research
Patent

Seronegative spondyloarthropathy diagnosis and treatment (WO/2015/010744)

Team: Immunoregulation
Project leader: Lars Rogge
Member: Elisabetta Bianchi
Scientific Fields
Diseases
Organisms
Applications
Technique
Starting Date
28
Jul 2015
Status
Ongoing
Members
2
Structures
1

About

Methods of diagnosing a spondylarthritis (SpA) or a likelihood of having or developing an SpA ina subjectare provided. The methods may comprise performing a genotyping assay of (i) at least one first SNP locus linked to a first gene selected from IL23R,  IL12B, STAT3, STAT4, and CCR6, and (ii) at least one second SNP locus linked to a second gene selected from IL23R, IL12B, STAT3, STAT4, and CCR6. Methodsof treating or preventing an SpA in a subjectare also provided. The methods may comprise performing a genotyping assay of (i) at least one first SNP locus linked to a first gene selected from IL23R, IL12B, STAT3, STAT4, and CCR6, and (ii) at least one second SNP locus linked to a second gene selected from IL23R, IL12B, STAT3, STAT4, and CCR6. Kits for performing the genotyping assays are also provided.