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© Liliana Mancio, Institut Pasteur
Primary human hepatocytes co-cultured with parenchymal cells at 6 days post-seeding. The expression of human CD81 is depicted in pink
Scientific Fields
Diseases
Organisms
Applications
Technique

About

One of the things that fascinate me the most in life is black holes. I have so much knowledge about them that one can assume I majored in astrophysics. However, I accepted long ago that my mathematical gene was degraded, and what was left from it was the multiplication table. But this is not a sad story, as I have found a more complicated earthly model: Plasmodium. This parasite alters your perspective of time, where one day is made of 48 hours rather than 24. Moreover, the genome of Plasmodium is far more complicated than the Kerr-Newman metric. I started my adventure in Plasmodium research as an intern in 2019. I worked on studying the effect of a human compound on the parasite epigenome. I decided later on to pursue a PhD in Plasmodium and drug development, which opened a whole new world to me, and my fascination kept growing bigger and bigger until I reached the point of no return. After mastering the intra-erythrocytic cycle, I wanted to dig deeper into the other stages of the parasite. In 2024, I joined the team of Liliana Mancio Silva as a postdoc to uncover Plasmodium and the chamber of secrets, liver edition.

CV

Work Experience 

  • 2024-Present         Plasmodium Infection and Transmission, Post Doc, Institut Pasteur, France
  • 2020-2023              Laboratory of Host Pathogen Immunity (LPHI), PhD, Montpellier University, France
    “A unique Mechanism of Action of an Acyclic Nucleoside Phosphonate as Potent Inhibitor of Malaria Parasite Egress”
  • 02/2019-08/2019   Laboratory of Host-Parasite Interactions (BIHP), M2 Intern, Institut Pasteur, France
    “Investigating the Effect of human DNA Methyltransferase Inhibitors on Plasmodium falciparum