I am a first year PhD student in Han Li’s team, and I am studying the impacts of partial reprogramming on cellular senescence in vitro. Previously as an intern, I have worked on several projects that are related to ageing, which is my domain of interest. Here in my PhD, I will investigate how do senescent Mouse Embryonic Fibroblats might react to a short-term OSKM (Oct4, Sox2, Klf4, c-Myc, aka Yamanaka’s factors) expression, which have been demonstrated to reduce the senescence load in vivo, but we don’t know the mechanism.