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© Jacob SEELER & Anne DEJEAN, Institut Pasteur
Immunostaining of PML nuclear bodies involved in acute promyelocytic leukemia
Scientific Fields
Diseases
Organisms
Applications
Technique

Projects

Project
Ongoing
7 Members

Integrating the activities of SUMO in gene expression, inflammation and cancer (ERC-2011-AdG SUMOSTRESS)

Anne Dejean (PI)

Sumoylation of proteins has emerged as a central regulatory mechanism influencing a wide range of cellular processes and is notably a key pathway facilitating cellular response to stress. Gene expression appears to be particularly […]
Project
Ongoing
7 Members

Chromatin role of SUMO in oncogenesis

Anne Dejean (PI)

Like cellular reprogramming to stem cell fates, tumorigenesis is characterized by dysregulated cellular plasticity which facilitates the emergence of cancer cells, their survival and metastatic escape from the tumoral environment. While the contribution of […]
Project
Ongoing
10 Members

Deconstructing the role of SUMO on chromatin in cell identity and tissue repair (ERC-2018-AdG SUMiDENTITY)

Anne Dejean (PI)

The maintenance of cell identity and how it is subverted in disease are central questions in biology and medicine. The interplay between transcription factor and chromatin configurations plays a key role in maintaining cellular […]

Publications

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