Intestinal epithelial cell-parasite cross-talk during giardiasis induces an anti-inflammatory state | Research - Institut Pasteur

A little guide for advanced search:

Tip 1. You can use quotes "" to search for an exact expression.
Example: "cell division"
Tip 2. You can use + symbol to restrict results containing all words.
Example: +cell +stem
Tip 3. You can use + and - symbols to force inclusion or exclusion of specific words.
Example: +cell -stem

e.g. searching for members in projects tagged cancer

Search for

Count

IN

OUT

Content 1

Content Type

member
team
department
center
program_project
nrc
whocc
project
software
tool
patent

Keywords

Positions

Administrative Staff
Assistant Professor
Associate Professor
Clinical Research Assistant
Clinical Research Nurse
Clinician Researcher
Department Manager
Dual-education Student
Full Professor
Honorary Professor
Lab assistant
Master Student
Non-permanent Researcher
Nursing Staff
Permanent Researcher
Pharmacist
PhD Student
Physician
Post-doc
Prize
Project Manager
Research Associate
Research Engineer
Retired scientist
Technician
Undergraduate Student
Veterinary
Visiting Scientist

Appointments

Deputy Director of Center
Deputy Director of Department
Deputy Director of National Reference Center
Deputy Head of Facility
Director of Center
Director of Department
Director of Institute
Director of National Reference Center
Group Leader
Head of Facility
Head of Operations
Head of Structure
Honorary President of the Departement
Labex Coordinator

Content 2

Content Type

member
team
department
center
program_project
nrc
whocc
project
software
tool
patent

Keywords

Positions

Administrative Staff
Assistant Professor
Associate Professor
Clinical Research Assistant
Clinical Research Nurse
Clinician Researcher
Department Manager
Dual-education Student
Full Professor
Honorary Professor
Lab assistant
Master Student
Non-permanent Researcher
Nursing Staff
Permanent Researcher
Pharmacist
PhD Student
Physician
Post-doc
Prize
Project Manager
Research Associate
Research Engineer
Retired scientist
Technician
Undergraduate Student
Veterinary
Visiting Scientist

Appointments

Deputy Director of Center
Deputy Director of Department
Deputy Director of National Reference Center
Deputy Head of Facility
Director of Center
Director of Department
Director of Institute
Director of National Reference Center
Group Leader
Head of Facility
Head of Operations
Head of Structure
Honorary President of the Departement
Labex Coordinator

Search

EN
FR

Go back

Scroll to top

5th school of bioinformatics AVIESAN-IFB

Vivax sporozoite transcriptome: role of epigenetics in transcriptional regulation

Scientific Fields

Diseases

Organisms

Applications

Technique

Date

14

Oct 2016

Time

15:45:00

Institut Pasteur, Rue du Docteur Roux, Paris, France

Address

Building: Lwoff

Location

2016-10-14 15:45:00 2016-10-14 16:30:00 Europe/Paris Intestinal epithelial cell-parasite cross-talk during giardiasis induces an anti-inflammatory state Staffan SVÄRD – Department of Cell and Molecular Biology, Uppsala University (Uppsala – Suède) Abstract: Giardia intestinalis is a major cause of diarrhea but half of the infected remain asymptomatic. The mechanisms of disease […] Institut Pasteur, Rue du Docteur Roux, Paris, France

About

Staffan SVÄRD – Department of Cell and Molecular Biology, Uppsala University (Uppsala – Suède)

Abstract: Giardia intestinalis is a major cause of diarrhea but half of the infected remain asymptomatic. The mechanisms of disease remain poorly defined but no major intestinal tissue destruction and inflammation is induced. The parasite has even been suggested to be protective against other intestinal infections that cause severe inflammation in the intestine. To better understand the crosstalk between G. intestinalis and human intestinal epithelial cells, and especially the low level of inflammation, we studied gene expression in human intestinal epithelial cells and the parasite secretome during interaction in vitro. Interactions between Giardia trophozoites and host intestinal epithelial cells induce specific responses in both cell types. These responses can explain the low levels of inflammation during Giardia infections and it suggests how the diarrhea-causing parasite Giardia can be protective against other diarrheal diseases.

Biosketch: Dr. Staffan Svärd is currently Professor of Eukaryotic Microbiology at Department of Cell and Molecular Biology (ICM), Uppsala University, Sweden. Since 2011 he is also the Head of Department of ICM. Dr. Svärd did his PhD on catalytic RNAs and started to work on protozoan parasites as a post-doc in San Diego in the mid 90’s. The main research interest of Dr. Svärd since this time has been studies of the Biology and pathogenesis of Giardia inestinalis. Giardia is an intestinal parasite that currently induces 200 million cases of symptomatic diarrheal disease world-wide. The main focus of the Svärd research group is studies of host-parasite interactions using various omics techniques.

Contact: Ivo MUELLER (ivo.mueller@pasteur.fr – Poste 94.59)

Location

Building: Lwoff
Address: Institut Pasteur, Rue du Docteur Roux, Paris, France

Published on: 05 Oct 2016 • Modified on: 25 Sep 2017

(function($) { /* * render_map * * This function will render a Google Map onto the selected jQuery element * * @type function * @date 8/11/2013 * @since 4.3.0 * * @param $el (jQuery element) * @return n/a */ function render_map( $el ) { var MY_MAPTYPE_ID = 'custom_style'; var featureOpts = [{"stylers":[{"hue":"#0088ff"}]}]; var styledMapOptions = { name: 'Custom Style' }; var customMapType = new google.maps.StyledMapType(featureOpts, styledMapOptions); // var var $markers = $el.find('.marker'); // vars var args = { zoom : 16, scrollwheel : false, center : new google.maps.LatLng(0, 0), mapTypeId : google.maps.MapTypeId.ROADMAP, mapTypeId : MY_MAPTYPE_ID }; // create map var map = new google.maps.Map( $el[0], args); map.mapTypes.set(MY_MAPTYPE_ID, customMapType); // add a markers reference map.markers = []; // add markers $markers.each(function(){ add_marker( $(this), map ); }); // center map center_map( map ); } /* * add_marker * * This function will add a marker to the selected Google Map * * @type function * @date 8/11/2013 * @since 4.3.0 * * @param $marker (jQuery element) * @param map (Google Map object) * @return n/a */ function add_marker( $marker, map ) { // var var latlng = new google.maps.LatLng( $marker.attr('data-lat'), $marker.attr('data-lng') ); //var image = 'https://research.pasteur.fr/wp-content/themes/biologyx2/images/logomap.png'; var myIcon = new google.maps.MarkerImage('https://research.pasteur.fr/wp-content/themes/biologyx2/images/map-pin.png', null, null, null, new google.maps.Size(32,32)); // create marker var marker = new google.maps.Marker({ position : latlng, map : map, icon : myIcon }); // add to array map.markers.push( marker ); // if marker contains HTML, add it to an infoWindow if( $marker.html() ) { // create info window var infowindow = new google.maps.InfoWindow({ content : $marker.html() }); // show info window when marker is clicked google.maps.event.addListener(marker, 'click', function() { infowindow.open( map, marker ); }); } } /* * center_map * * This function will center the map, showing all markers attached to this map * * @type function * @date 8/11/2013 * @since 4.3.0 * * @param map (Google Map object) * @return n/a */ function center_map( map ) { // vars var bounds = new google.maps.LatLngBounds(); // loop through all markers and create bounds $.each( map.markers, function( i, marker ){ var latlng = new google.maps.LatLng( marker.position.lat(), marker.position.lng() ); bounds.extend( latlng ); }); // only 1 marker? if( map.markers.length == 1 ) { // set center of map map.setCenter( bounds.getCenter() ); map.setZoom( 15 ); } else { // fit to bounds map.fitBounds( bounds ); } } /* * document ready * * This function will render each map when the document is ready (page has loaded) * * @type function * @date 8/11/2013 * @since 5.0.0 * * @param n/a * @return n/a */ $(document).ready(function(){ $('.acf-map').each(function(){ render_map( $(this) ); }); }); })(jQuery);