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  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Clinical Research Nurse
  • Clinician Researcher
  • Department Manager
  • Dual-education Student
  • Full Professor
  • Honorary Professor
  • Lab assistant
  • Master Student
  • Non-permanent Researcher
  • Nursing Staff
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Prize
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
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© Research
Scientific Fields
Diseases
Organisms
Applications
Technique
Starting Date
26
Oct 2015
Keywords
2 Keywords
Status
Ongoing
Members
1
Structures
1
Instituts
1

About

We recently proposed that specific targeting of PP2A holoenzymes by viral proteins is a general biological strategy, used by various viruses (from DNA tumour viruses to HIV-1) to specifically deregulate intracellular pathways of their hosts. Based on a recent patented observation we proposed a new hypothesis named “The Quinta Columna theory”. This scientific hypothesis predicts that the presence of virally-encoded PP2A-binding sequences in biological fluids of infected patients may deregulate PP2A-dependent homeostasis.This ongoing project is based on development of an ELISA test to analyze the presence of specific viral sequences in biological fluids (serum, and if possible CSF) (see also fig. below). 

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