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© Research
Publication : Journal of clinical microbiology

Fatal invasive infection with fungemia due to Microascus cirrosus after heart and lung transplantation in a patient with cystic fibrosis

Team: Archived: Molecular Mycology
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of clinical microbiology - 04 May 2011

Miossec C, Morio F, Lepoivre T, Le Pape P, Garcia-Hermoso D, Gay-Andrieu F, Haloun A, Treilhaud M, Leclair F, Miegeville M

Link to Pubmed [PMID] – 21543579

J. Clin. Microbiol. 2011 Jul;49(7):2743-7

Scopulariopsis species are rarely but increasingly recognized as opportunistic pathogens in immunocompromised patients. We report on a patient suffering from cystic fibrosis who developed disseminated fungal infection due to a rare Scopulariopsis species, Microascus cirrosus, after heart and lung transplantation. Despite antifungal combination therapy with voriconazole and caspofungin, the patient died 4 weeks after transplantation. Diagnostic difficulties and optimal management of disseminated Scopulariopsis/Microascus infections are discussed.