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© Research
Publication : Journal of bacteriology

ClpP of Streptococcus salivarius is a novel member of the dually regulated class of stress response genes in gram-positive bacteria

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of bacteriology - 01 Jan 2003

Chastanet A, Msadek T

Link to Pubmed [PMID] – 12511518

J. Bacteriol. 2003 Jan;185(2):683-7

Nucleotide sequence analysis of the Streptococcus salivarius clpP locus revealed potential binding sites for both the CtsR and HrcA repressors. Dual regulation by HrcA and CtsR was demonstrated by using Bacillus subtilis as a heterologous host, and CtsR was shown to bind directly to the clpP promoter sequence. This is the first example of a clpP gene under the control of HrcA.