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© Research
Publication : PloS one

Harnessing naturally occurring tumor immunity: a clinical vaccine trial in prostate cancer

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in PloS one - 01 Sep 2010

Frank MO, Kaufman J, Tian S, Suárez-Fariñas M, Parveen S, Blachère NE, Morris MJ, Slovin S, Scher HI, Albert ML, Darnell RB

Link to Pubmed [PMID] – 20824184

PLoS ONE 2010;5(9)

Studies of patients with paraneoplastic neurologic disorders (PND) have revealed that apoptotic tumor serves as a potential potent trigger for the initiation of naturally occurring tumor immunity. The purpose of this study was to assess the feasibility, safety, and immunogenicity of an apoptotic tumor-autologous dendritic cell (DC) vaccine.