Interactions of attenuated Mycobacterium tuberculosis phoP mutant with human macrophages

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Deputy Director of Department
Deputy Director of National Reference Center
Deputy Head of Facility
Director of Center
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Group Leader
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Honorary President of the Departement
Labex Coordinator

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The stromal gene encoding the CD274 antigen as a genetic modifier controlling survival of mice with γ-radiation-induced T-cell lymphoblastic lymphomas.

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Published in PloS one - 24 Sep 2010

Ferrer NL, Gomez AB, Neyrolles O, Gicquel B, Martin C

Link to Pubmed [PMID] – 20885976

PLoS ONE 2010;5(9):e12978

Mycobacterium tuberculosis phoP mutant SO2 derived from a clinical isolate was shown to be attenuated in mouse bone marrow-derived macrophages and in vivo mouse infection model and has demonstrated a high potential as attenuated vaccine candidate against tuberculosis.

Published on: 24 Sep 2010