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The canonical genetic code contains 61 sense and 3 nonsense (stop) codons. Although it is almost universal, about 60 different genetic code variants have been described so far. Majority of these alterations evolved in protists, with ciliates being their most frequent bearers. I will describe general reasons behind the alterations of genetic code, and what is known about the reassignment of all three stop codons into sense codons in the trypanosomatid flagellate Blastocrithidia. I will also try to draw some conclusions that may be of wider importance for our understanding of genetic codes.
Link to your website: INSTITUTE OF PARASITOLOGY | Profil

