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© Benoît Chassaing
Interaction microbiote-mucus à la surface de l’épithélium colique humain
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Cell host & microbe - 12 Oct 2022

Chassaing B

Link to Pubmed [PMID] – 36228581

Link to DOI – 10.1016/j.chom.2022.09.009

Cell Host Microbe 2022 Oct; 30(10): 1345-1346

Loss-of-function mutations in NOD2, a receptor-sensing microbiota-derived muropeptides, is a genetic predisposition for Crohn’s disease (CD). In this issue of Cell Host & Microbe, Gao et al. (2022) identify a microbiota-derived peptidoglycan remodeling enzyme that dampens chronic intestinal inflammation via NOD2, offering a potential path to alleviate CD.