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© Benoît Chassaing
Interaction microbiote-mucus à la surface de l’épithélium colique humain
Publication : Mucosal immunology

Host/microbiota interactions in health and diseases-Time for mucosal microbiology!

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Mucosal immunology - 01 Sep 2021

Daniel N, Lécuyer E, Chassaing B

Link to Pubmed [PMID] – 33772148

Link to DOI – 10.1038/s41385-021-00383-w

Mucosal Immunol 2021 Sep; 14(5): 1006-1016

During the last 20 years, a new field of research delineating the importance of the microbiota in health and diseases has emerged. Inappropriate host-microbiota interactions have been shown to trigger a wide range of chronic inflammatory diseases, and defining the exact mechanisms behind perturbations of such relationship, as well as ways by which these disturbances can lead to disease states, both remain to be fully elucidated. The mucosa-associated microbiota constitutes a recently studied microbial population closely linked with the promotion of chronic intestinal inflammation and associated disease states. This review will highlight seminal works that have brought into light the importance of the mucosa-associated microbiota in health and diseases, emphasizing the challenges and promises of expending the mucosal microbiology field of research.