Timeline

21 Feb 2019

event

François Jacob Conference

17 Jan 2018

publication

A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies

27 Sep 2017

publication

Two independent modes of chromatin organization revealed by cohesin removal

05 Dec 2016

publication

The Shh Topological Domain Facilitates the Action of Remote Enhancers by Reducing the Effects of Genomic Distances

05 Oct 2016

publication

Formation of new chromatin domains determines pathogenicity of genomic duplications

27 Jun 2016

publication

Gene regulation at a distance: from remote enhancers to 3D regulatory ensembles

11 Apr 2016

publication

Cis-regulatory architecture of a brain signaling center predates the origin of chordates

12 Nov 2015

publication

Gene regulation during development in the light of topologically associating domains

22 May 2015

publication

Model mice for 15q11-13 duplication syndrome exhibit late-onset obesity and altered lipid metabolism

29 Jan 2015

publication

Hoxa2 selectively enhances Meis binding to change a branchial arch ground state

08 Jan 2015

publication

A discrete transition zone organizes the topological and regulatory autonomy of the adjacent tfap2c and bmp7 genes

05 Jun 2014

publication

The architecture of gene expression: integrating dispersed cis-regulatory modules into coherent regulatory domains

25 May 2014

publication

Long-range enhancers regulating Myc expression are required for normal facial morphogenesis

07 Jan 2014

publication

Functional and topological characteristics of mammalian regulatory domains

18 Sep 2013

publication

Efficient site-specific transgenesis and enhancer activity tests in medaka using PhiC31 integrase

01 Jun 2013

publication

A switch between topological domains underlies HoxD genes collinearity in mouse limbs

06 May 2013

publication

From remote enhancers to gene regulation: charting the genome’s regulatory landscapes

02 Apr 2013

publication

TRACER: a resource to study the regulatory architecture of the mouse genome

28 Feb 2013

publication

An integrated holo-enhancer unit defines tissue and gene specificity of the Fgf8 regulatory landscape

01 Feb 2013

publication

Phenotypic impact of genomic structural variation: insights from and for human disease

07 Aug 2012

publication

Transcription factors: from enhancer binding to developmental control

23 Nov 2011

publication

A regulatory archipelago controls Hox genes transcription in digits

20 Mar 2011

publication

Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor

29 Dec 2010

publication

A systematic enhancer screen using lentivector transgenesis identifies conserved and non-conserved functional elements at the Olig1 and Olig2 locus

14 Jan 2010

publication

KAP1 controls endogenous retroviruses in embryonic stem cells

01 Jan 2010

publication

Control of vertebrate Hox clusters by remote and global cis-acting regulatory sequences

06 Mar 2009

publication

Uncoupling time and space in the collinear regulation of Hox genes

16 Dec 2008

publication

Analysis of mammalian gene batteries reveals both stable ancestral cores and highly dynamic regulatory sequences

07 May 2008

publication

Genotypic features of lentivirus transgenic mice

05 Apr 2008

publication

Characterization of mouse Dactylaplasia mutations: a model for human ectrodactyly SHFM3

01 Jan 2008

publication

Global control regions and regulatory landscapes in vertebrate development and evolution

23 Mar 2007

publication

Transgenic analysis of Hoxd gene regulation during digit development

03 Jul 2005

publication

Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes

01 Jul 2004

publication

Six1 and Eya1 expression can reprogram adult muscle from the slow-twitch phenotype into the fast-twitch phenotype

15 Jun 2004

publication

Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression

01 May 2003

publication

A global control region defines a chromosomal regulatory landscape containing the HoxD cluster

01 Oct 2002

publication

Fiber-type specific and position-dependent expression of a transgene in limb muscles

01 Apr 2002

publication

A t(2;8) balanced translocation with breakpoints near the human HOXD complex causes mesomelic dysplasia and vertebral defects

01 Sep 2001

publication

Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations

13 Oct 2000

publication

The alpha subunits of Gz and Gi interact with the eyes absent transcription cofactor Eya2, preventing its interaction with the six class of homeodomain-containing proteins

18 Jun 1999

publication

Developmental regulation of the aldolase A muscle-specific promoter during in vivo muscle maturation is controlled by a nuclear receptor binding element

24 Nov 1998

publication

Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site

12 Jun 1998

publication

Proximal sequences of the aldolase A fast muscle-specific promoter direct nerve- and activity-dependent expression in transgenic mice

01 Mar 1998

publication

The human pH aldolase A promoter directs widespread but muscle-predominant expression in transgenic mice

01 Jan 1998

publication

A binding site for nuclear receptors is required for the differential expression of the aldolase A fast-twitch muscle promoter in body and head muscles

01 Feb 1997

publication

A combination of MEF3 and NFI proteins activates transcription in a subset of fast-twitch muscles

13 Oct 1995

publication

Myotube-specific activity of the human aldolase A M-promoter requires an overlapping binding site for NF1 and MEF2 factors in addition to a binding site (M1) for unknown proteins

A little guide for advanced search:

François Jacob Conference

A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies

Two independent modes of chromatin organization revealed by cohesin removal

The Shh Topological Domain Facilitates the Action of Remote Enhancers by Reducing the Effects of Genomic Distances

Formation of new chromatin domains determines pathogenicity of genomic duplications

Gene regulation at a distance: from remote enhancers to 3D regulatory ensembles

Cis-regulatory architecture of a brain signaling center predates the origin of chordates

Gene regulation during development in the light of topologically associating domains

Model mice for 15q11-13 duplication syndrome exhibit late-onset obesity and altered lipid metabolism

Hoxa2 selectively enhances Meis binding to change a branchial arch ground state

A discrete transition zone organizes the topological and regulatory autonomy of the adjacent tfap2c and bmp7 genes

The architecture of gene expression: integrating dispersed cis-regulatory modules into coherent regulatory domains

Long-range enhancers regulating Myc expression are required for normal facial morphogenesis

Functional and topological characteristics of mammalian regulatory domains

Efficient site-specific transgenesis and enhancer activity tests in medaka using PhiC31 integrase

A switch between topological domains underlies HoxD genes collinearity in mouse limbs

From remote enhancers to gene regulation: charting the genome’s regulatory landscapes

TRACER: a resource to study the regulatory architecture of the mouse genome

An integrated holo-enhancer unit defines tissue and gene specificity of the Fgf8 regulatory landscape

Phenotypic impact of genomic structural variation: insights from and for human disease

Transcription factors: from enhancer binding to developmental control

A regulatory archipelago controls Hox genes transcription in digits

Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor

A systematic enhancer screen using lentivector transgenesis identifies conserved and non-conserved functional elements at the Olig1 and Olig2 locus

KAP1 controls endogenous retroviruses in embryonic stem cells

Control of vertebrate Hox clusters by remote and global cis-acting regulatory sequences

Uncoupling time and space in the collinear regulation of Hox genes

Analysis of mammalian gene batteries reveals both stable ancestral cores and highly dynamic regulatory sequences

Genotypic features of lentivirus transgenic mice

Characterization of mouse Dactylaplasia mutations: a model for human ectrodactyly SHFM3

Global control regions and regulatory landscapes in vertebrate development and evolution

Transgenic analysis of Hoxd gene regulation during digit development

Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes

Six1 and Eya1 expression can reprogram adult muscle from the slow-twitch phenotype into the fast-twitch phenotype

Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression

A global control region defines a chromosomal regulatory landscape containing the HoxD cluster

Fiber-type specific and position-dependent expression of a transgene in limb muscles

A t(2;8) balanced translocation with breakpoints near the human HOXD complex causes mesomelic dysplasia and vertebral defects

Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations

The alpha subunits of Gz and Gi interact with the eyes absent transcription cofactor Eya2, preventing its interaction with the six class of homeodomain-containing proteins

Developmental regulation of the aldolase A muscle-specific promoter during in vivo muscle maturation is controlled by a nuclear receptor binding element

Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site

Proximal sequences of the aldolase A fast muscle-specific promoter direct nerve- and activity-dependent expression in transgenic mice

The human pH aldolase A promoter directs widespread but muscle-predominant expression in transgenic mice

A binding site for nuclear receptors is required for the differential expression of the aldolase A fast-twitch muscle promoter in body and head muscles

A combination of MEF3 and NFI proteins activates transcription in a subset of fast-twitch muscles

Myotube-specific activity of the human aldolase A M-promoter requires an overlapping binding site for NF1 and MEF2 factors in addition to a binding site (M1) for unknown proteins