Timeline

26 Jan 2021

publication

Core-Modified Coelenterazine Luciferin Analogues: Synthesis and Chemiluminescence Properties.

22 Sep 2020

publication

Influenza A virus co-opts ERI1 exonuclease bound to histone mRNA to promote viral transcription.

16 Jul 2020

project

Identification of cellular PDZ-containing Proteins targeted by the virus SARS-Cov-2 during infection (PPCOVi)

22 Oct 2019

event

Virology Department Seminar: “Mechanism of epigenetic variability in clonal cell lineages” with Alexander Gimelbrant

07 Jun 2018

event

“Network Medicine: From Cellular Networks to the Human Diseasome” Virology & C3BI seminar with Albert-Lazlo Barabasi

06 Feb 2018

publication

The SRC-family tyrosine kinase HCK shapes the landscape of SKAP2 interactome

23 Nov 2017

publication

Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT

11 Oct 2017

event

C3BI Seminar – Systems biology seminars

13 Apr 2017

event

Pr Frederick P. ROTH – VIROLOGY DEPARTMENT SEMINAR

07 Sep 2015

tool

Optogenetic “Cre-stiching” strategy for barcode fusion genetics

07 Sep 2015

tool

High-throughput protein-protein interaction assay based on a split-luciferase

04 Sep 2015

project

Interplay between influenza virus and the ubiquitin/proteasome system

04 Sep 2015

project

Multi-species mapping of influenza viruses cellular targets using high-throughput complementary strategies in a “One Health” perspective.

04 Sep 2015

project

Comparative interactomics of filoviridae (Task Force Ebola WP6.2)

18 Aug 2015

project

Design and optimization of new bioluminescent systems better-suited to in cellulo and in vivo conditions

17 Jun 2015

publication

Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other

08 Jun 2015

publication

Quantifying domain-ligand affinities and specificities by high-throughput holdup assay

27 May 2015

publication

Targeting the Two Oncogenic Functional Sites of the HPV E6 Oncoprotein with a High-Affinity Bivalent Ligand

23 Apr 2015

publication

Widespread macromolecular interaction perturbations in human genetic disorders

01 Jan 2015

publication

A field-proven yeast two-hybrid protocol used to identify coronavirus-host protein-protein interactions

11 Dec 2014

publication

Microtubule-associated proteins 1 (MAP1) promote human immunodeficiency virus type I (HIV-1) intracytoplasmic routing to the nucleus

01 Sep 2014

publication

Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage.

12 Jun 2014

publication

Recruitment of RED-SMU1 complex by Influenza A Virus RNA polymerase to control Viral mRNA splicing

03 Oct 2013

publication

Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity

01 Oct 2013

publication

Exploration of binary virus-host interactions using an infectious protein complementation assay.

18 Jul 2013

publication

A comparative approach to characterize the landscape of host-pathogen protein-protein interactions

01 Jun 2013

publication

Species-specific impact of the autophagy machinery on Chikungunya virus infection.

21 Feb 2013

publication

EVER2 protein binds TRADD to promote TNF-α-induced apoptosis

14 Jan 2013

publication

The V protein of Tioman virus is incapable of blocking type I interferon signaling in human cells

16 Aug 2012

publication

Identification and targeting of an interaction between a tyrosine motif within hepatitis C virus core protein and AP2M1 essential for viral assembly

08 Aug 2012

publication

Comparative analysis of virus-host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase

28 Jun 2012

publication

Large scale genotype comparison of human papillomavirus E2-host interaction networks provides new insights for e2 molecular functions

13 Jun 2012

publication

HMGB1 protein binds to influenza virus nucleoprotein and promotes viral replication

01 Mar 2012

publication

Mapping of Chikungunya virus interactions with host proteins identified nsP2 as a highly connected viral component.

29 Nov 2011

publication

Benchmarking a luciferase complementation assay for detecting protein complexes

17 Nov 2011

publication

Inhibition of influenza virus replication by constrained peptides targeting nucleoprotein

12 Sep 2011

publication

The potassium-chloride cotransporter 2 promotes cervical cancer cell migration and invasion by an ion transport-independent mechanism

08 Dec 2009

publication

ViralORFeome: an integrated database to generate a versatile collection of viral ORFs.

18 Sep 2009

publication

Differential regulation of type I interferon and epidermal growth factor pathways by a human Respirovirus virulence factor

12 Aug 2009

publication

Peptides that mimic the amino-terminal end of the rabies virus phosphoprotein have antiviral activity

22 Jun 2009

publication

Polo-like kinase 1 (PLK1) regulates interferon (IFN) induction by MAVS

01 Jun 2009

publication

The EVER proteins as a natural barrier against papillomaviruses: a new insight into the pathogenesis of human papillomavirus infections

12 Nov 2008

publication

Inhibition of IFN-alpha/beta signaling by two discrete peptides within measles virus V protein that specifically bind STAT1 and STAT2

04 Nov 2008

publication

Hepatitis C virus infection protein network

13 Oct 2008

publication

Monitoring of chloride and activity of glycine receptor channels using genetically encoded fluorescent sensors

17 Jun 2008

publication

Inhibition of Chikungunya virus infection in cultured human muscle cells by furin inhibitors: impairment of the maturation of the E2 surface glycoprotein

05 Mar 2008

publication

Mitochondrial dysfunction in lyssavirus-induced apoptosis

06 Jan 2008

publication

Genetically encoded chloride indicator with improved sensitivity

01 Jan 2008

publication

A SAP30 complex inhibits IFN-beta expression in Rift Valley fever virus infected cells

24 Dec 2007

publication

Regulation of cellular zinc balance as a potential mechanism of EVER-mediated protection against pathogenesis by cutaneous oncogenic human papillomaviruses

07 Aug 2007

publication

Measles virus V protein blocks Jak1-mediated phosphorylation of STAT1 to escape IFN-alpha/beta signaling

07 Feb 2007

publication

Rabies virus matrix protein interplay with eIF3, new insights into rabies virus pathogenesis

04 Oct 2006

publication

Human papillomavirus type 5 E6 oncoprotein represses the transforming growth factor beta signaling pathway by binding to SMAD3

01 May 2006

publication

Cottontail rabbit papillomavirus E8 protein is essential for wart formation and provides new insights into viral pathogenesis

01 Jan 2006

publication

Rabies: epidemiological tendencies and control tools

17 Apr 2005

publication

A variant in the CD209 promoter is associated with severity of dengue disease

01 Jul 2004

publication

Antiviral drug discovery strategy using combinatorial libraries of structurally constrained peptides

15 Aug 2003

publication

Targeting of incoming retroviral Gag to the centrosome involves a direct interaction with the dynein light chain 8

01 Feb 2002

publication

A novel expression cassette of lyssavirus shows that the distantly related Mokola virus can rescue a defective rabies virus genome

01 Jan 2002

publication

Integrated version of reverse two-hybrid system for the postproteomic era

01 Nov 2001

publication

Molecular basis for the interaction between rabies virus phosphoprotein P and the dynein light chain LC8: dissociation of dynein-binding properties and transcriptional functionality of P

01 Jan 2000

publication

A little guide for advanced search:

Core-Modified Coelenterazine Luciferin Analogues: Synthesis and Chemiluminescence Properties.

Influenza A virus co-opts ERI1 exonuclease bound to histone mRNA to promote viral transcription.

Identification of cellular PDZ-containing Proteins targeted by the virus SARS-Cov-2 during infection (PPCOVi)

Virology Department Seminar: “Mechanism of epigenetic variability in clonal cell lineages” with Alexander Gimelbrant

“Network Medicine: From Cellular Networks to the Human Diseasome” Virology & C3BI seminar with Albert-Lazlo Barabasi

The SRC-family tyrosine kinase HCK shapes the landscape of SKAP2 interactome

Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT

C3BI Seminar – Systems biology seminars

Pr Frederick P. ROTH – VIROLOGY DEPARTMENT SEMINAR

Optogenetic “Cre-stiching” strategy for barcode fusion genetics

High-throughput protein-protein interaction assay based on a split-luciferase

Interplay between influenza virus and the ubiquitin/proteasome system

Multi-species mapping of influenza viruses cellular targets using high-throughput complementary strategies in a “One Health” perspective.

Comparative interactomics of filoviridae (Task Force Ebola WP6.2)

Design and optimization of new bioluminescent systems better-suited to in cellulo and in vivo conditions

Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other

Quantifying domain-ligand affinities and specificities by high-throughput holdup assay

Targeting the Two Oncogenic Functional Sites of the HPV E6 Oncoprotein with a High-Affinity Bivalent Ligand

Widespread macromolecular interaction perturbations in human genetic disorders

A field-proven yeast two-hybrid protocol used to identify coronavirus-host protein-protein interactions

Microtubule-associated proteins 1 (MAP1) promote human immunodeficiency virus type I (HIV-1) intracytoplasmic routing to the nucleus

Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage.

Recruitment of RED-SMU1 complex by Influenza A Virus RNA polymerase to control Viral mRNA splicing

Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity

Exploration of binary virus-host interactions using an infectious protein complementation assay.

A comparative approach to characterize the landscape of host-pathogen protein-protein interactions

Species-specific impact of the autophagy machinery on Chikungunya virus infection.

EVER2 protein binds TRADD to promote TNF-α-induced apoptosis

The V protein of Tioman virus is incapable of blocking type I interferon signaling in human cells

Identification and targeting of an interaction between a tyrosine motif within hepatitis C virus core protein and AP2M1 essential for viral assembly

Comparative analysis of virus-host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase

Large scale genotype comparison of human papillomavirus E2-host interaction networks provides new insights for e2 molecular functions

HMGB1 protein binds to influenza virus nucleoprotein and promotes viral replication

Mapping of Chikungunya virus interactions with host proteins identified nsP2 as a highly connected viral component.

Benchmarking a luciferase complementation assay for detecting protein complexes

Inhibition of influenza virus replication by constrained peptides targeting nucleoprotein

The potassium-chloride cotransporter 2 promotes cervical cancer cell migration and invasion by an ion transport-independent mechanism

ViralORFeome: an integrated database to generate a versatile collection of viral ORFs.

Differential regulation of type I interferon and epidermal growth factor pathways by a human Respirovirus virulence factor

Peptides that mimic the amino-terminal end of the rabies virus phosphoprotein have antiviral activity

Polo-like kinase 1 (PLK1) regulates interferon (IFN) induction by MAVS

The EVER proteins as a natural barrier against papillomaviruses: a new insight into the pathogenesis of human papillomavirus infections

Inhibition of IFN-alpha/beta signaling by two discrete peptides within measles virus V protein that specifically bind STAT1 and STAT2

Hepatitis C virus infection protein network

Monitoring of chloride and activity of glycine receptor channels using genetically encoded fluorescent sensors

Inhibition of Chikungunya virus infection in cultured human muscle cells by furin inhibitors: impairment of the maturation of the E2 surface glycoprotein

Mitochondrial dysfunction in lyssavirus-induced apoptosis

Genetically encoded chloride indicator with improved sensitivity

A SAP30 complex inhibits IFN-beta expression in Rift Valley fever virus infected cells

Regulation of cellular zinc balance as a potential mechanism of EVER-mediated protection against pathogenesis by cutaneous oncogenic human papillomaviruses

Measles virus V protein blocks Jak1-mediated phosphorylation of STAT1 to escape IFN-alpha/beta signaling

Rabies virus matrix protein interplay with eIF3, new insights into rabies virus pathogenesis

Human papillomavirus type 5 E6 oncoprotein represses the transforming growth factor beta signaling pathway by binding to SMAD3

Cottontail rabbit papillomavirus E8 protein is essential for wart formation and provides new insights into viral pathogenesis

Rabies: epidemiological tendencies and control tools

A variant in the CD209 promoter is associated with severity of dengue disease

Antiviral drug discovery strategy using combinatorial libraries of structurally constrained peptides

Targeting of incoming retroviral Gag to the centrosome involves a direct interaction with the dynein light chain 8

A novel expression cassette of lyssavirus shows that the distantly related Mokola virus can rescue a defective rabies virus genome

Integrated version of reverse two-hybrid system for the postproteomic era

Molecular basis for the interaction between rabies virus phosphoprotein P and the dynein light chain LC8: dissociation of dynein-binding properties and transcriptional functionality of P

DNA-based immunisation against rabies and rabies-related viruses: towards multivalent vaccines