Timeline
07 Apr 2023
publication
Fumarate as positive modulator of allosteric transitions in the pentameric ligand-gated ion channel GLIC: Requirement of an intact vestibular pocket.
Read more09 Apr 2018
publication
Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation
Read more27 Dec 2017
publication
Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel
Read more04 May 2016
publication
Emerging Molecular Mechanisms of Signal Transduction in Pentameric Ligand-Gated Ion Channels
Read more23 Dec 2013
publication
Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation
Read more11 Jul 2012
publication
Synthesis of selective agonists for the α7 nicotinic acetylcholine receptor with in situ click-chemistry on acetylcholine-binding protein templates
Read more28 Jun 2012
publication
The effect of crebanine on memory and cognition impairment via the alpha-7 nicotinic acetylcholine receptor
Read more06 Apr 2012
publication
Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template
Read more18 Oct 2011
publication
Creating an α7 nicotinic acetylcholine recognition domain from the acetylcholine-binding protein: crystallographic and ligand selectivity analyses
Read more28 Jan 2011
publication