Ligne de temps
Stéphane Bretagne
Directeur(trice) Adjoint(e) de Centre National de Référence
14 Jun 2022
news
Important publication by the French National Reference Center for Invasive Mycoses & Antifungals summarizing 7 years of nationwide surveillance of these severe infections
Lire plus17 May 2022
publication
Echinocandins Susceptibility Patterns of 2,787 Yeast Isolates: Importance of the Thresholds for the Detection of FKS Mutations.
Lire plus02 May 2022
publication
Active Surveillance Program to Increase Awareness on Invasive Fungal Diseases: the French RESSIF Network (2012 to 2018).
Lire plus25 Jan 2022
news
Highlighted Publication: “Combination of mycological criteria: a better surrogate to identify COVID-19 associated pulmonary aspergillosis patients and evaluate prognosis?” Dellière et al., J. Clin Microbiol, Molecular Mycology team
Lire plus05 Jan 2022
publication
Combination of mycological criteria: a better surrogate to identify COVID-19 associated pulmonary aspergillosis patients and evaluate prognosis?
Lire plus24 Nov 2021
publication
Cerebral aspergillosis in the era of new antifungals: The CEREALS national cohort study Nationwide CEREbral Aspergillosis Lesional study (CEREALS).
Lire plus20 Oct 2021
publication
COVID-19-Associated Pulmonary Aspergillosis, Fungemia, and Pneumocystosis in the Intensive Care Unit: a Retrospective Multicenter Observational Cohort during the First French Pandemic Wave.
Lire plus14 Sep 2021
01 Sep 2021
publication
Earliest case of Candida auris infection imported in 2007 in Europe from India prior to the 2009 description in Japan.
Lire plus22 May 2021
publication
Different repartition of the cryptic species of black aspergilli according to the anatomical sites in human infections, in a French University hospital.
Lire plus20 Apr 2021
publication
Prospective comparison of (1,3)-beta-D-glucan detection using colorimetric and turbidimetric assays for diagnosing invasive fungal disease.
Lire plus05 Apr 2021
publication
Azole Susceptibility Profiles of More than 9,000 Clinical Yeast Isolates Belonging to 40 Common and Rare Species.
Lire plus09 Mar 2021
08 Mar 2021
publication
New clinical algorithm including fungal biomarkers to better diagnose probable invasive pulmonary aspergillosis in ICU.
Lire plus01 Jan 2021
publication
Species-Specific Immunological Reactivities Depend on the Cell-Wall Organization of the Two Aspergillus, Aspergillus fumigatus and A. flavus.
Lire plus01 Jan 2021
publication
No Impact of Fluconazole to Echinocandins Replacement as First-Line Therapy on the Epidemiology of Yeast Fungemia (Hospital-Driven Active Surveillance, 2004-2017, Paris, France).
Lire plus13 Dec 2020
publication
Risk factors associated with COVID-19-associated pulmonary aspergillosis in ICU patients: a French multicentric retrospective cohort.
Lire plus01 Sep 2020
publication
Invasive Infections with Nannizziopsis obscura Species Complex in 9 Patients from West Africa, France, 2004-20201.
Lire plus18 Aug 2020
publication
Correlation Between Pneumocystis jirovecii Mitochondrial Genotypes and High and Low Fungal Loads Assessed by Single Nucleotide Primer Extension Assay and Quantitative Real-Time PCR.
Lire plus05 Aug 2020
publication
Entamoeba histolytica DNA Detection in Serum of Suspected Amoebic Liver Abscess.
Lire plus01 Aug 2020
publication
The Fungal PCR Initiative’s evaluation of in-house and commercial Pneumocystis jirovecii qPCR assays: Toward a standard for a diagnostics assay.
Lire plus01 Jan 2020
publication
Comparison of MultiLocus Sequence Typing (MLST) and Microsatellite Length Polymorphism (MLP) for Pneumocystis jirovecii genotyping.
Lire plus01 Apr 2019
publication
Primary antifungal prophylaxis with micafungin after allogeneic hematopoietic stem cell transplantation: a monocentric prospective study.
Lire plus01 Mar 2019
publication
Outcome and potentially modifiable risk factors for candidemia in critically ill burns patients: A matched cohort study.
Lire plus14 Feb 2019
publication
Isavuconazole MIC distribution of 29 yeast species responsible for invasive infections (2015-2017)
Lire plus07 Feb 2019
28 Jan 2019
23 Jan 2019
project
Molecular variability of Pneumocystis jirovecii: from genotype to antigenic variability
Lire plus27 Sep 2018
publication
Mainly Post-Transplant Factors Are Associated with Invasive Aspergillosis after Allogeneic Stem Cell Transplantation: A Study from the Surveillance des Aspergilloses Invasives en France and Société Francophone de Greffe de Moelle et de Thérapie Cellulaire
Lire plus12 Jul 2018
publication
Failure of voriconazole therapy due to acquired azole resistance in Aspergillus fumigatus in a kidney transplant recipient with chronic necrotizing aspergillosis.
Lire plus01 May 2018
publication
In Vitro and In Vivo Efficacy of a Novel and Long-Acting Fungicidal Azole, PC1244, on Aspergillus fumigatus Infection.
Lire plus24 Apr 2018
publication
Outbreak of Invasive Wound Mucormycosis in a Burn Unit Due to Multiple Strains of Mucor circinelloides f. circinelloides Resolved by Whole-Genome Sequencing.
Lire plus12 Apr 2018
publication
From phaeohyphomycosis to disseminated chromoblastomycosis: A retrospective study of infections caused by dematiaceous fungi
Lire plus16 Nov 2017
publication
Population Structure of Candida parapsilosis: No Genetic Difference Between French and Uruguayan Isolates Using Microsatellite Length Polymorphism
Lire plus01 Nov 2017
publication
A cell impedance-based real-time in vitro assay to assess the toxicity of amphotericin B formulations.
Lire plus01 Jul 2017
publication
Continuous increase of Trichophyton tonsurans as a cause of tinea capitis in the urban area of Paris, France: a 5-year-long study.
Lire plus01 May 2017
publication
In Vitro and In Vivo Antifungal Profile of a Novel and Long-Acting Inhaled Azole, PC945, on Aspergillus fumigatus Infection.
Lire plus01 Apr 2017
publication
Pneumocystis jirovecii pneumonia: still a concern in patients with haematological malignancies and stem cell transplant recipients-authors’ response.
Lire plus20 Mar 2017
publication
The risk and clinical outcome of candidemia depending on underlying malignancy
Lire plus05 Mar 2017
publication
Predisposing factors and outcome of uncommon yeast species-related fungaemia based on an exhaustive surveillance programme (2002-14)
Lire plus01 Jan 2017
21 Nov 2016
15 Nov 2016
publication
Detection of Circulating Mucorales DNA in Critically Ill Burn Patients: Preliminary Report of a Screening Strategy for Early Diagnosis and Treatment.
Lire plus01 Sep 2016
publication
Early diagnosis and monitoring of mucormycosis by detection of circulating DNA in serum: retrospective analysis of 44 cases collected through the French Surveillance Network of Invasive Fungal Infections (RESSIF).
Lire plus01 Aug 2016
publication
New therapeutic strategies for invasive aspergillosis in the era of azole resistance: how should the prevalence of azole resistance be defined?
Lire plus01 Aug 2016
publication
Variation in copy number of the 28S rDNA of Aspergillus fumigatus measured by droplet digital PCR and analog quantitative real-time PCR.
Lire plus01 Jan 2016
publication
Copy Number Variation of Mitochondrial DNA Genes in Pneumocystis jirovecii According to the Fungal Load in BAL Specimens.
Lire plus01 Jan 2016
publication
Typing Candida Species Using Microsatellite Length Polymorphism and Multilocus Sequence Typing
Lire plus01 Jan 2016
publication
Diversity of Pneumocystis jirovecii during Infection Revealed by Ultra-Deep Pyrosequencing.
Lire plus01 Jan 2016
publication
Fluconazole and Echinocandin Resistance of Candida glabrata Correlates Better with Antifungal Drug Exposure Rather than with MSH2 Mutator Genotype in a French Cohort of Patients Harboring Low Rates of Resistance.
Lire plus01 Dec 2015
publication
[Cryptococcus where they are not expected: Five case reports of extra-cerebral and extra-pulmonary cryptococcosis].
Lire plus15 Oct 2015
publication
Whole genome sequencing to investigate an outbreak of mucormycosis in a burn unit
Lire plus01 Sep 2015
publication
Absence of Fungal Spore Internalization by Bronchial Epithelium in Mouse Models Evidenced by a New Bioimaging Approach and Transmission Electronic Microscopy.
Lire plus01 Sep 2015
publication
High diversity of non-sporulating moulds in respiratory specimens of immunocompromised patients: should all the species be reported when diagnosing invasive aspergillosis?
Lire plus31 Aug 2015
publication
Épidémie de mucormycose dans un centre de traitement des brûlés : des biomarqueurs diagnostiques au séquençage complets des souches
Lire plus14 Jul 2015
14 Jul 2015
01 Jul 2015
publication
Cutaneous Invasive Aspergillosis: Retrospective Multicenter Study of the French Invasive-Aspergillosis Registry and Literature Review
Lire plus25 Jun 2015
publication
Aspergillus Polymerase Chain Reaction: Systematic Review of Evidence for Clinical Use in Comparison With Antigen Testing
Lire plus17 Jun 2015
publication
Clinical Performance of Aspergillus PCR for Testing Serum and Plasma: a Study by the European Aspergillus PCR Initiative
Lire plus17 Jun 2015
publication
Analytical Comparison of In Vitro-Spiked Human Serum and Plasma for PCR-Based Detection of Aspergillus fumigatus DNA: a Study by the European Aspergillus PCR Initiative
Lire plus14 Jun 2015
09 Jun 2015
publication
Cryptococcosis Serotypes Impact Outcome and Provide Evidence of Cryptococcus neoformans Speciation
Lire plus11 May 2015
11 May 2015
22 Apr 2015
publication
Dual Invasive Infection with Phaeoacremonium parasiticum and Paraconiothyrium cyclothyrioides in a Renal Transplant Recipient: Case Report and Comprehensive Review of the Literature of Phaeoacremonium Phaeohyphomycosis.
Lire plus01 Jan 2015
publication
Posttraumatic mucormycosis: a nationwide study in France and review of the literature
Lire plus01 Jan 2015
publication
Importance of operational factors in the reproducibility of Aspergillus galactomannan enzyme immune assay.
Lire plus06 Aug 2014
publication
Worrisome trends in incidence and mortality of candidemia in intensive care units (Paris area, 2002-2010)
Lire plus12 Jul 2014
publication
Breakthrough invasive fungal disease in patients receiving posaconazole primary prophylaxis: a 4-year study
Lire plus01 Jun 2014
publication
Difficulties with molecular diagnostic tests for mould and yeast infections: where do we stand?
Lire plus20 May 2014
publication
Longer incubation times for yeast fungemia: importance for presumptive treatment
Lire plus10 May 2014
publication
Iterative breakthrough invasive aspergillosis due to TR(34) /L98H azole-resistant Aspergillus fumigatus and Emericella sublata in a single hematopoietic stem cell transplant patient
Lire plus19 Feb 2014
publication
Azole-resistant Aspergillus fumigatus isolate with the TR34/L98H mutation in both a fungicide-sprayed field and the lung of a hematopoietic stem cell transplant recipient with invasive aspergillosis
Lire plus28 Jan 2014
publication
Antifungal pre-emptive strategy for high-risk neutropenic patients: why the story is still ongoing
Lire plus19 Nov 2013
publication
Direct genotyping of Toxoplasma gondii from amniotic fluids based on B1 gene polymorphism using minisequencing analysis.
Lire plus01 Sep 2013
publication
Incidence and risk factors of Legionella pneumophila pneumonia during anti-tumor necrosis factor therapy: a prospective French study
Lire plus03 Aug 2013
publication
Bacteremia in patients receiving TNF-alpha antagonists–a prospective multicenter study
Lire plus14 Jun 2013
publication
Performance of serum biomarkers for the early detection of invasive aspergillosis in febrile, neutropenic patients: a multi-state model
Lire plus11 Jun 2013
publication
Metabolic detoxification pathways for 5-methoxy-sterigmatocystin in primary tracheal epithelial cells
Lire plus09 May 2013
publication
Fungal infections after liver transplantation: outcomes and risk factors revisited in the MELD era
Lire plus24 Apr 2013
publication
Development and evaluation of a calibrator material for nucleic acid-based assays for diagnosing aspergillosis
Lire plus04 Feb 2013
publication
Aspergillus endocarditis in the era of new antifungals: major role for antigen detection
Lire plus21 Nov 2012
publication
A new workflow for the microbiological diagnosis of febrile neutropenia in patients with a central venous catheter
Lire plus24 Aug 2012
17 Jul 2012
publication
Aerosolized liposomal amphotericin B: prediction of lung deposition, in vitro uptake and cytotoxicity
Lire plus17 Jul 2012
publication
Outcomes associated with amphotericin B lipid complex (ABLC) prophylaxis in high-risk liver transplant patients
Lire plus18 Jun 2012
15 May 2012
publication
Decreasing incidence of cryptococcal meningitis in West Africa in the era of highly active antiretroviral therapy
Lire plus11 May 2012
publication
High prevalence of triazole resistance in Aspergillus fumigatus, especially mediated by TR/L98H, in a French cohort of patients with cystic fibrosis
Lire plus20 Apr 2012
publication
Association between circulating DNA, serum (1->3)-β-D-glucan, and pulmonary fungal burden in Pneumocystis pneumonia
Lire plus15 Feb 2012
publication
Temporal similarity between Candida albicans genotypes in a Tunisian neonatal intensive care unit suggests several nosocomial cross-contamination episodes
Lire plus13 Feb 2012
01 Feb 2012
18 Jan 2012
publication
Variation of B1 gene and AF146527 repeat element copy numbers according to Toxoplasma gondii strains assessed using real-time quantitative PCR
Lire plus01 Jan 2012
07 Dec 2011
publication
Clinical significance of quantifying Pneumocystis jirovecii DNA by using real-time PCR in bronchoalveolar lavage fluid from immunocompromised patients
Lire plus01 Nov 2011
publication
Imported acquired immunodeficiency syndrome-related histoplasmosis in metropolitan France: a comparison of pre-highly active anti-retroviral therapy and highly active anti-retroviral therapy eras
Lire plus15 Oct 2011
publication
Contribution of uniformly 13C-enriched sterigmatocystin to the study of its pulmonary metabolism
Lire plus21 Sep 2011
19 Sep 2011
publication
ECIL recommendations for the use of biological markers for the diagnosis of invasive fungal diseases in leukemic patients and hematopoietic SCT recipients
Lire plus20 Jul 2011
publication
Increased mortality in young candidemia patients associated with presence of a Candida albicans general-purpose genotype
Lire plus20 Jul 2011
01 Jul 2011
publication
Genotyping of the protozoan pathogen Toxoplasma gondii using high-resolution melting analysis of the repeated B1 gene
Lire plus16 Jun 2011
publication
Variable beta-glucans production by different states of Eurotium amstelodami explains differences in inflammatory responses in airway cells
Lire plus10 Jun 2011
publication
Epidemiological trends in invasive aspergillosis in France: the SAIF network (2005-2007)
Lire plus20 Apr 2011
publication
Cytochrome b gene quantitative PCR for diagnosing Plasmodium falciparum infection in travelers
Lire plus01 Apr 2011
01 Feb 2011
21 Dec 2010
publication
Drug-specific risk of non-tuberculosis opportunistic infections in patients receiving anti-TNF therapy reported to the 3-year prospective French RATIO registry
Lire plus08 Dec 2010
publication
The use of mannan antigen and anti-mannan antibodies in the diagnosis of invasive candidiasis: recommendations from the Third European Conference on Infections in Leukemia
Lire plus05 Dec 2010
publication
Low prevalence of resistance to azoles in Aspergillus fumigatus in a French cohort of patients treated for haematological malignancies.
Lire plus30 Nov 2010
publication
Molecular survey of rodent-borne Trypanosoma in Niger with special emphasis on T. lewisi imported by invasive black rats
Lire plus15 Nov 2010
publication
Recent exposure to caspofungin or fluconazole influences the epidemiology of candidemia: a prospective multicenter study involving 2,441 patients
Lire plus11 Nov 2010
publication
Impact of invasive fungal disease on the chemotherapy schedule and event-free survival in acute leukemia patients who survived fungal disease: a case-control study
Lire plus01 Nov 2010
01 Nov 2010
publication
New evidence of the involvement of Lichtheimia corymbifera in farmer’s lung disease
Lire plus18 Oct 2010
publication
Degradation of fungal DNA in formalin-fixed paraffin-embedded sinus fungal balls hampers reliable sequence-based identification of fungi
Lire plus08 Oct 2010
publication
Severe imported falciparum malaria: a cohort study in 400 critically ill adults
Lire plus07 Oct 2010
publication
Metabolic detoxication pathways for sterigmatocystin in primary tracheal epithelial cells
Lire plus18 Aug 2010
publication
Critical stages of extracting DNA from Aspergillus fumigatus in whole-blood specimens
Lire plus18 Aug 2010
26 Jul 2010
publication
European guidelines for antifungal management in leukemia and hematopoietic stem cell transplant recipients: summary of the ECIL 3–2009 update
Lire plus07 Jul 2010
publication
Primary in vitro culture of porcine tracheal epithelial cells in an air-liquid interface as a model to study airway epithelium and Aspergillus fumigatus interactions
Lire plus01 May 2010
publication
Yeast contamination of kidney, liver and cardiac preservation solutions before graft: need for standardisation of microbial evaluation
Lire plus28 Apr 2010
publication
Multicenter collaborative study for standardization of Candida albicans genotyping using a polymorphic microsatellite marker
Lire plus07 Apr 2010
publication