Laboratoire

Génétique Moléculaire des Virus à ARN

Responsable

Sylvie Van Der Werf

CNRS Paris 7 UMR3569

Département de Virologie

Virus Influenzae [Centre de Référence]

• Cell biology and molecular transport mechanisms
• Epidemiology and public health
• Evolution
• Genetics, Genomics
• Host-pathogen interactions
• Interactomics
• Molecular interactions
• Replication
• RNA synthesis, processing, modification and degradation
• Systems biology
• Virology
• Cancer
• Hepatitis C
• Hepatocellular carcinoma
• Names of infectious diseases
• Influenza
• Virus diseases
• GB virus (GBV-B)
• Hepatitis A virus (HAV)
• Hepatitis C virus (HCV)
• Influenza virus
• MERS-Corona Virus
• SARS virus
• Virus

VOIR TOUSFermer

Présentation

Groupes

Group

Sylvie Van Der Werf

Groupe : Sylvie van der Werf

Group

Nadia Naffakh

Interactions entre le virus de la grippe et la cellule hôte

Group

Annette Martin

Interactions Hepacivirus – hôte

Group

Yves Jacob

Virus interactomics

Membres

Sylvie Van Der Werf

Responsable de Structure

Responsable

Mathilde Ben Assaya

Technicien(ne)

Andreea Alexandru

Stéphane Leandri

Camille Berthault

Marion Declercq

Melanie Dos Santos

Marie Lazzerini

Brigitte Blumen

Malika Hocine

Christine Detchepare

Camille Roquin

Vincent Enouf

Directeur(trice) Adjoint(e) de Centre National de Référence

Sylvie Behillil

Nadia Naffakh

Chef(fe) de Groupe

Florian Andrieux

Cyril Barbezange

Post-doctorant(e)

Caroline Demeret

Guillaume Fournier

Post-doctorant(e)

Sandie Munier

Bernadette Crescenzo

Ingénieur(e) de Recherche

Julie Magnus

Ingénieur(e) de Recherche

Lisette Cohen

Matthieu Fritz

Etudiant(e) en thèse

Patricia Cassonnet

Ingénieur(e) de Recherche

Stéphanie Aicher

Etudiant(e) en thèse

Elise Biquand

Etudiant(e) en thèse

Cédric Diot

Etudiant(e) en thèse

Yves Jacob

Chef(fe) de Groupe

Annette Martin

Chef(fe) de Groupe

Anciens Membres

Nicolas Escriou

Malika Gouali

Cyril Barbezange

Anna Kostrzak

Claire Denis

David Briand

Sylvie Laganier

Sébastien Le Gal

Valérie Lorin

François Rimlinger

Vanessa Roca

Grands Projets

Institut Carnot Pasteur MS

Le label Carnot vise à reconnaître la 
capacité de structures de recherche à collaborer avec des partenaires socio-
économiques, notamment des entreprises, tout en renforçant leur visibilité. Un institut Canot (IC) labélisé bénéficie de moyens […]

Projets

Role of PDZ-binding motif from Flavivirus non-structural proteins in flaviviral life cycle

Arthropod-borne viruses (arboviruses) include numerous human and animal pathogens that are important global health threats. Flaviviruses are arboviruses belonging to the Flaviviridae family. They include neurotropic viruses such as West Nile (WNV), Japanese encephalitis […]

The European Virus Archive Goes Global

The European Virus Archive now goes global and become EVAg as a continuation of EVA within the Horizon 2020 programme .The new EVAg consortium (25 institution from 19 countries, EU and non-EU ) is […]

Epidemiology and evolution of respiratory viruses

  Research in this area is strongly linked to the activities of the National Influenza Reference Center (NIC) and WHO Reference Laboratory for H5 and SARS-CoV viruses, associated to the unit. We contribute to […]

Publications

• 2016
  Time-Resolved Visualisation of Nearly-Native Influenza A Virus Progeny Ribonucleoproteins and Their Individual Components in Live Infected Cells - Avilov S, Magnus J, Cusack S, Naffakh N - PloS one
• 2016
  Targeting host calpain proteases decreases influenza A virus infection - Blanc F, Furio L, Moisy D, Yen HL, Chignard M, Letavernier E, Naffakh N, Mok CK, Si-Tahar M - American journal of physiology. Lung cellular and molecular physiology
• 2015
  Early estimates of 2014/15 seasonal influenza vaccine effectiveness in preventing influenza-like illness in general practice using the screening method in France - Souty C, Blanchon T, Bonmarin I, Lévy-Bruhl D, Behillil S, Enouf V, Valette M, Bouscambert M, Turbelin C, Capai L, Roussel V, Hanslik T, Falchi A - Human vaccines & immunotherapeutics
• 2015
  Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other - Butkinaree C, Canuel M, Essalmani R, Poirier S, Benjannet S, Asselin MC, Roubtsova A, Hamelin J, Marcinkiewicz J, Chamberland A, Guillemot J, Mayer G, Sisodia SS, Jacob Y, Prat A, Seidah NG - The Journal of biological chemistry
• 2015
  Quantifying domain-ligand affinities and specificities by high-throughput holdup assay - Vincentelli R, Luck K, Poirson J, Polanowska J, Abdat J, Blémont M, Turchetto J, Iv F, Ricquier K, Straub ML, Forster A, Cassonnet P, Borg JP, Jacob Y, Masson M, Nominé Y, Reboul J, Wolff N, Charbonnier S, Travé G - Nature methods
• 2015
  Targeting the Two Oncogenic Functional Sites of the HPV E6 Oncoprotein with a High-Affinity Bivalent Ligand - Ramirez J, Poirson J, Foltz C, Chebaro Y, Schrapp M, Meyer A, Bonetta A, Forster A, Jacob Y, Masson M, Deryckère F, Travé G - Angewandte Chemie (International ed. in English)
• 2015
  Erratum to: Genetic Adaptation of Influenza A Viruses in Domestic Animals and Their Potential Role in Interspecies Transmission: A Literature Review - Munoz O, De Nardi M, van der Meulen K, van Reeth K, Koopmans M, Harris K, von Dobschuetz S, Freidl G, Meijer A, Breed AC, Hill A, Kosmider R, Banks J, Stärk KD, Wieland B, Stevens K, van der Werf S, Enouf V, Dauphin G, Dundon W, Cattoli G, Capua I, - EcoHealth
• 2015
  Widespread macromolecular interaction perturbations in human genetic disorders - Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kovács IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, Khurana V, Sharma A, Liu YY, Yachie N, Zhong Q, Shen Y, Palagi A, San-Miguel A, Fan C, Balcha D, Dricot A, Jordan DM, Walsh JM, Shah AA, Yang X, Stoyanova AK, Leighton A, Calderwood MA, Jacob Y, Cusick ME, Salehi-Ashtiani K, Whitesell LJ, Sunyaev S, Berger B, Barabási AL, Charloteaux B, Hill DE, Hao T, Roth FP, Xia Y, Walhout AJ, Lindquist S, Vidal M - Cell
• 2015
  Temperature-Sensitive Mutants in the Influenza A Virus RNA Polymerase: Alterations in the PA Linker Reduce Nuclear Targeting of the PB1-PA Dimer and Result in Viral Attenuation - Da Costa B, Sausset A, Munier S, Ghounaris A, Naffakh N, Le Goffic R, Delmas B - Journal of virology
• 2015
  Start of the 2014/15 influenza season in Europe: drifted influenza A(H3N2) viruses circulate as dominant subtype - Broberg E, Snacken R, Adlhoch C, Beauté J, Galinska M, Pereyaslov D, Brown C, Penttinen P, - Euro surveillance : bulletin Européen sur les maladies transmissibles = European communicable disease bulletin
• +
  Voir la liste complète de publications

Contact

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Address
25-28 Rue du Docteur Roux
75015, Paris
France