Génétique du Paludisme et Résistance

Erythrocyte invasion is a complex process involving multiple interactions between Plasmodium merozoites and host erythrocytes. Unlike P. falciparum, which can use multiple erythrocyte receptors for invasion and has merozoite proteins with overlapping and redundant […]

More sensitive and specific malaria RDTs based on the detection of new biomarkers of Plasmodium infections, implementable in the field (as point-of-care), have to be developed. The objective of these new tools would allow […]

Our knowledge on P. falciparum drug resistance has considerably progressed, particularly with the discovery of molecular markers associated to artemisinin derivatives and partner drugs (piperaquine, mefloquine) resistances. However, the race between effective antimalarial treatments […]